4ii9 A 1.66 BS01 peptide B 0 W32 K36 H139 Q143 I208 T209 R211 Y215 Y256 W32 K36 H139 Q143 I208 T209 R211 Y215 Y256 K36 D108 R211 F304 K305 E319 K36 D108 R211 F304 K305 E319 2.3.2.10 0008360,0009252,0016746,0016755,0044038,0047206,0071555 Q9EY50 23744707 3 ~ 7 PVLNLNDPQAVERYEEFMRQSPYGQVTQDLGWAKVKNNWEPVDVYLEDDQGAIIAAMSMLLGDTPTDKKFAYASKGPVMDVTDVDLLDRLVDEAVKALDGRAYVLRFDPEVAYSDEFNTTLQDHGYVTRNRNVADAGMHATIQPRLNMVLDLTKFPDAKTTLDLYPSKTKSKIKRPFRDGVEVHSGNSATELDEFFKTYTTMAERHGITHRPIEYFQRMQAAFDADTMRIFVAEREGKLLSTGIALKYGRKIWYMYAGSMDGNTYYAPYAVQSEMIQWALDTNTDLYDLGGIESESTDDSLYVFKHVFVKDAPREYIGEIDKVLDPEVYAELVKDGH 4ii9 A 1.66 BS02 rna C 0 M202 H206 A257 S259 P268 G291 S300 K305 M202 H206 A257 S259 P268 G291 S300 K305 K36 D108 R211 F304 K305 E319 K36 D108 R211 F304 K305 E319 2.3.2.10 0008360,0009252,0016746,0016755,0044038,0047206,0071555 Q9EY50 23744707 8 ~ 10 PVLNLNDPQAVERYEEFMRQSPYGQVTQDLGWAKVKNNWEPVDVYLEDDQGAIIAAMSMLLGDTPTDKKFAYASKGPVMDVTDVDLLDRLVDEAVKALDGRAYVLRFDPEVAYSDEFNTTLQDHGYVTRNRNVADAGMHATIQPRLNMVLDLTKFPDAKTTLDLYPSKTKSKIKRPFRDGVEVHSGNSATELDEFFKTYTTMAERHGITHRPIEYFQRMQAAFDADTMRIFVAEREGKLLSTGIALKYGRKIWYMYAGSMDGNTYYAPYAVQSEMIQWALDTNTDLYDLGGIESESTDDSLYVFKHVFVKDAPREYIGEIDKVLDPEVYAELVKDGH 4ii9 A 1.66 BS03 UDP B 1 K36 W39 F70 Y103 I142 R211 K36 W39 F70 Y103 I142 R211 K36 D108 R211 F304 K305 E319 K36 D108 R211 F304 K305 E319 2.3.2.10 0008360,0009252,0016746,0016755,0044038,0047206,0071555 -logKd/Ki=6.03, IC50=0.93uM Q9EY50 23744707 101 PVLNLNDPQAVERYEEFMRQSPYGQVTQDLGWAKVKNNWEPVDVYLEDDQGAIIAAMSMLLGDTPTDKKFAYASKGPVMDVTDVDLLDRLVDEAVKALDGRAYVLRFDPEVAYSDEFNTTLQDHGYVTRNRNVADAGMHATIQPRLNMVLDLTKFPDAKTTLDLYPSKTKSKIKRPFRDGVEVHSGNSATELDEFFKTYTTMAERHGITHRPIEYFQRMQAAFDADTMRIFVAEREGKLLSTGIALKYGRKIWYMYAGSMDGNTYYAPYAVQSEMIQWALDTNTDLYDLGGIESESTDDSLYVFKHVFVKDAPREYIGEIDKVLDPEVYAELVKDGH