4hys A 2.415 BS01 peptide B 0 D112 R127 Y130 S161 D162 C163 V323 W324 E329 D105 R120 Y123 S154 D155 C156 V293 W294 E299 D151 K153 N156 D169 T188 D144 K146 N149 D162 T166 2.7.11.24 0004672,0004707,0005524,0006468 P45983 23352510 154 ~ 162 NNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPREHTIEEWKELIYKEVM 4hys A 2.415 BS02 1BJ A 1 V40 A53 E109 L110 M111 L168 V33 A46 E102 L103 M104 L161 D151 K153 N156 D169 T188 D144 K146 N149 D162 T166 2.7.11.24 0004672,0004707,0005524,0006468 ic50=0.055uM -logKd/Ki=7.26, IC50=0.055uM P45983 23352510 401 NNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPREHTIEEWKELIYKEVM