4hwo A 1.907 BS01 ZN A 1 C334 H385 H511 C93 H144 H270 C334 R363 Q381 D383 H385 K465 H511 C93 R122 Q140 D142 H144 K224 H270 6.1.1.3 0000166,0004812,0004829,0005524,0005737,0006418,0006435 P0A8M3 23362938 701 RDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEELEHHHHHH 4hwo A 1.907 BS02 409 A 1 R363 E365 M374 R375 V376 F379 Q381 D383 H385 Y462 K465 Q479 T482 Q484 H511 G516 S517 R520 R122 E124 M133 R134 V135 F138 Q140 D142 H144 Y221 K224 Q238 T241 Q243 H270 G275 S276 R279 C334 R363 Q381 D383 H385 K465 H511 C93 R122 Q140 D142 H144 K224 H270 6.1.1.3 0000166,0004812,0004829,0005524,0005737,0006418,0006435 Ki=2.9nM -logKd/Ki=8.54, Ki=2.9nM P0A8M3 23362938 702 RDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEELEHHHHHH