4gzx A 2.45 BS01 SIA E 1 R118 E119 R152 R224 E276 R292 R371 Y406 R37 E38 R71 R143 E195 R211 R290 Y325 G151 E277 R292 R371 Y406 G70 E196 R211 R290 Y325 3.2.1.18 0004308,0005975,0016020,0016798,0020002,0033644,0044423,0046761,0046872,0052794,0052795,0052796,0055036 -logKd/Ki=3.19, Kd=645uM K7N5N3 23015718 2 AEYRNWSKPQCDITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPDKCYQFALGQGTTLNNVHSNNTVRGRTPYRTLLMNELGVPFHLGTKQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYNGRLVDSVVSWSKEILRTQESECVCINGTCTVVMTDGSASGKADTKILFIEEGKIVHTSTLSGSAQHVEECSCYPRYPGVRCVCRDNWKGSNRPIVDINIKDHSIVSSYVCSGLVGDTPRKNDSSSSSHCLDPNNEEGGHGVKGWAFDDGNDVWMGRTINETSRLGYETFKVIEGWSNPKSKLQINRQVIVDRGNRSGYSGIFSVEGKSCINRCFYVELIRGRKEETEVLWTSNSIVVFCGTSGTYGTGSWPDGADLNLMPI 4gzx A 2.45 BS02 CA A 1 D293 G297 D324 G345 G346 H347 D212 G216 D243 G264 G265 H266 G151 E277 R292 R371 Y406 G70 E196 R211 R290 Y325 3.2.1.18 0004308,0005975,0016020,0016798,0020002,0033644,0044423,0046761,0046872,0052794,0052795,0052796,0055036 K7N5N3 23015718 812 AEYRNWSKPQCDITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPDKCYQFALGQGTTLNNVHSNNTVRGRTPYRTLLMNELGVPFHLGTKQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYNGRLVDSVVSWSKEILRTQESECVCINGTCTVVMTDGSASGKADTKILFIEEGKIVHTSTLSGSAQHVEECSCYPRYPGVRCVCRDNWKGSNRPIVDINIKDHSIVSSYVCSGLVGDTPRKNDSSSSSHCLDPNNEEGGHGVKGWAFDDGNDVWMGRTINETSRLGYETFKVIEGWSNPKSKLQINRQVIVDRGNRSGYSGIFSVEGKSCINRCFYVELIRGRKEETEVLWTSNSIVVFCGTSGTYGTGSWPDGADLNLMPI