4ey7 A 2.3509 BS01 E20 A 1 Y72 W86 Y124 E202 W286 F295 Y337 F338 Y341 H447 Y69 W83 Y121 E199 W277 F286 Y328 F329 Y332 H438 G121 G122 G154 S203 A204 G242 F297 F299 E334 H447 G118 G119 G151 S200 A201 G239 F288 F290 E325 H438 3.1.1.7 0001507,0001540,0001919,0002076,0003990,0004104,0005515,0005518,0005576,0005604,0005615,0005634,0005794,0005886,0006581,0007155,0007399,0007416,0009986,0016020,0016787,0017171,0031594,0031623,0032223,0042166,0042802,0042803,0042982,0043083,0043236,0045202,0048471,0050714,0052689,0060041,0095500,0098552,0120162 IC50=10.0nM, Ki=20.5nM, EC50=43nM P22303 23035744 604 EDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSA