4ey6 A 2.3983 BS01 GNT A 1 W86 G120 G121 G122 Y124 E202 S203 F295 F297 Y337 F338 H447 W83 G117 G118 G119 Y121 E199 S200 F286 F288 Y328 F329 H438 G121 G122 G154 S203 A204 G242 F297 F299 E334 H447 G118 G119 G151 S200 A201 G239 F288 F290 E325 H438 3.1.1.7 0001507,0001540,0001919,0002076,0003990,0004104,0005515,0005518,0005576,0005604,0005615,0005634,0005794,0005886,0006581,0007155,0007399,0007416,0009986,0016020,0016787,0017171,0031594,0031623,0032223,0042166,0042802,0042803,0042982,0043083,0043236,0045202,0048471,0050714,0052689,0060041,0095500,0098552,0120162 IC50=800nM, Ki=62nM, EC50=1100nM P22303 23035744 604 EDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSA