4ekl A 2.0 BS01 0RF A 1 L156 G157 K158 G159 V164 A177 K179 E228 A230 E234 E278 M281 T291 F438 L13 G14 K15 G16 V21 A34 K36 E85 A87 E91 E135 M138 T148 F295 D274 K276 N279 D292 T312 D131 K133 N136 D149 T169 2.7.11.1 0004672,0004674,0005524,0006468 ic50=5nM IC50=2.60nM P31749 22569334 501 RVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPSMECVDSERRPHFPQFDYSASS