4e1e A 2.65 BS01 MG A 1 D98 D102 D97 D101 K48 H93 D98 D102 R107 D170 K207 F246 D250 D251 K47 H92 D97 D101 R106 D169 K206 F245 D249 D250 2.5.1.10 0004161,0004337,0004659,0005737,0008299,0016740,0016765,0045337,0046872 Q95WL3 22715997 402 ASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK 4e1e A 2.65 BS02 MG A 2 D98 D102 D97 D101 K48 H93 D98 D102 R107 D170 K207 F246 D250 D251 K47 H92 D97 D101 R106 D169 K206 F245 D249 D250 2.5.1.10 0004161,0004337,0004659,0005737,0008299,0016740,0016765,0045337,0046872 Q95WL3 22715997 403 ASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK 4e1e A 2.65 BS03 0MW A 1 Y94 D98 R107 Q167 K207 D250 K264 Y93 D97 R106 Q166 K206 D249 K263 K48 H93 D98 D102 R107 D170 K207 F246 D250 D251 K47 H92 D97 D101 R106 D169 K206 F245 D249 D250 2.5.1.10 0004161,0004337,0004659,0005737,0008299,0016740,0016765,0045337,0046872 -logKd/Ki=6.31, IC50=490nM Q95WL3 22715997 404 ASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK 4e1e A 2.65 BS04 IPE A 1 K48 R51 Q91 R108 F246 D250 K47 R50 Q90 R107 F245 D249 K48 H93 D98 D102 R107 D170 K207 F246 D250 D251 K47 H92 D97 D101 R106 D169 K206 F245 D249 D250 2.5.1.10 0004161,0004337,0004659,0005737,0008299,0016740,0016765,0045337,0046872 Q95WL3 22715997 405 ASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK