4b0o A 2.35 BS01 FUL B 1 L249 F278 L247 F276 G116 G117 G149 S198 A199 Y237 V288 F290 E325 H438 G114 G115 G147 S196 A197 Y235 V286 F288 E323 H436 3.1.1.8 0001540,0003824,0003990,0004104,0005515,0005576,0005615,0005641,0005783,0005788,0005886,0006581,0006805,0007584,0007612,0008285,0009410,0014016,0016486,0016788,0019695,0019899,0033265,0042802,0043279,0050783,0050805,0051384,0051593,0052689,0072562 P06276 22922115 3 DIIIATKNGKVRGMQLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPEQYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDQYTKAEEILSRSIVKRWANFAKYGNPQETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 4b0o A 2.35 BS02 GLY A 1 D129 K131 D127 K129 G116 G117 G149 S198 A199 Y237 V288 F290 E325 H438 G114 G115 G147 S196 A197 Y235 V286 F288 E323 H436 3.1.1.8 0001540,0003824,0003990,0004104,0005515,0005576,0005615,0005641,0005783,0005788,0005886,0006581,0006805,0007584,0007612,0008285,0009410,0014016,0016486,0016788,0019695,0019899,0033265,0042802,0043279,0050783,0050805,0051384,0051593,0052689,0072562 P06276 22922115 1296 DIIIATKNGKVRGMQLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPEQYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDQYTKAEEILSRSIVKRWANFAKYGNPQETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 4b0o A 2.35 BS03 CA A 1 T488 T508 T486 T506 G116 G117 G149 S198 A199 Y237 V288 F290 E325 H438 G114 G115 G147 S196 A197 Y235 V286 F288 E323 H436 3.1.1.8 0001540,0003824,0003990,0004104,0005515,0005576,0005615,0005641,0005783,0005788,0005886,0006581,0006805,0007584,0007612,0008285,0009410,0014016,0016486,0016788,0019695,0019899,0033265,0042802,0043279,0050783,0050805,0051384,0051593,0052689,0072562 P06276 22922115 1304 DIIIATKNGKVRGMQLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPEQYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDQYTKAEEILSRSIVKRWANFAKYGNPQETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV 4b0o A 2.35 BS04 15F A 1 W82 G117 P285 S287 F329 W430 M437 H438 W80 G115 P283 S285 F327 W428 M435 H436 G116 G117 G149 S198 A199 Y237 V288 F290 E325 H438 G114 G115 G147 S196 A197 Y235 V286 F288 E323 H436 3.1.1.8 0001540,0003824,0003990,0004104,0005515,0005576,0005615,0005641,0005783,0005788,0005886,0006581,0006805,0007584,0007612,0008285,0009410,0014016,0016486,0016788,0019695,0019899,0033265,0042802,0043279,0050783,0050805,0051384,0051593,0052689,0072562 Ki=7.3uM P06276 22922115 1307 DIIIATKNGKVRGMQLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAPKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPEQYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDQYTKAEEILSRSIVKRWANFAKYGNPQETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFFPKV