4au8 A 1.9 BS01 Z3R A 1 I10 V18 F80 C83 D84 Q85 D86 K89 L133 D144 I11 V19 F69 C72 D73 Q74 D75 K78 L122 D133 D126 K128 Q130 N131 D144 T164 D115 K117 Q119 N120 D133 T151 2.7.11.1 0000226,0000307,0001764,0001963,0002039,0004672,0004674,0004693,0005176,0005515,0005524,0005634,0005654,0005737,0005829,0005874,0005886,0006338,0006468,0006886,0006915,0007160,0007268,0007399,0007409,0007416,0007519,0008017,0008045,0008306,0008542,0014044,0014069,0016020,0016079,0016241,0016301,0016310,0016477,0016533,0018105,0018107,0019233,0021537,0021549,0021695,0021697,0021766,0021819,0021954,0021987,0022038,0030027,0030036,0030054,0030175,0030182,0030334,0030424,0030425,0030426,0030517,0030549,0030900,0031175,0031397,0031594,0031914,0032801,0035249,0035418,0042220,0042981,0042995,0043005,0043025,0043113,0043125,0043204,0043525,0044024,0045202,0045786,0045861,0045892,0045956,0046826,0048148,0048156,0048167,0048488,0048489,0048511,0048675,0048709,0048813,0050321,0051301,0051402,0051649,0051726,0051879,0051966,0060078,0060079,0061001,0070509,0090314,0098793,0106310,1903076,1903421,1904646 ic50=551nM -logKd/Ki=6.26, IC50=551nM Q00535 22889803 1293 GSQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVPSSALREICLLKELKHKNIVRLHDVLHKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDF