3tmz A 2.248 BS01 HEM A 1 R98 V113 I114 R125 A298 G299 T302 T303 V367 H369 F429 S430 R434 C436 L437 G438 A442 R70 V85 I86 R97 A269 G270 T273 T274 V338 H340 F400 S401 R405 C407 L408 G409 A413 T302 F429 C436 T273 F400 C407 1.14.14.1 0004497,0005506,0005737,0005783,0005789,0006805,0008392,0016020,0016705,0016712,0019373,0020037,0043231,0046872,0070330 P00178 22909231 501 GKLPPGPSPLPVLGNLLQMDKGLLRSFLRLREKYGDVFTVYLGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGERWRALRRFSLATMRDFMGKRSVEERIQEEARCLVEELRKSKGALLDNTLLFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFELFSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYLLRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPHVTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGALKRNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDIDLTPRESGVGNVPPSYQIRFLARH 3tmz A 2.248 BS02 CM5 A 1 F184 K186 V194 F244 F155 K157 V165 F215 T302 F429 C436 T273 F400 C407 1.14.14.1 0004497,0005506,0005737,0005783,0005789,0006805,0008392,0016020,0016705,0016712,0019373,0020037,0043231,0046872,0070330 P00178 22909231 502 GKLPPGPSPLPVLGNLLQMDKGLLRSFLRLREKYGDVFTVYLGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGERWRALRRFSLATMRDFMGKRSVEERIQEEARCLVEELRKSKGALLDNTLLFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFELFSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYLLRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPHVTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGALKRNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDIDLTPRESGVGNVPPSYQIRFLARH 3tmz A 2.248 BS03 06X A 1 I101 F206 F297 A298 T302 V477 I73 F177 F268 A269 T273 V448 T302 F429 C436 T273 F400 C407 1.14.14.1 0004497,0005506,0005737,0005783,0005789,0006805,0008392,0016020,0016705,0016712,0019373,0020037,0043231,0046872,0070330 ic50=2uM P00178 22909231 503 GKLPPGPSPLPVLGNLLQMDKGLLRSFLRLREKYGDVFTVYLGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGERWRALRRFSLATMRDFMGKRSVEERIQEEARCLVEELRKSKGALLDNTLLFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFELFSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYLLRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPHVTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGALKRNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDIDLTPRESGVGNVPPSYQIRFLARH 3tmz A 2.248 BS04 06X A 2 L51 L70 I101 I209 Q215 E218 F365 E387 V477 L23 L42 I73 I180 Q186 E189 F336 E358 V448 T302 F429 C436 T273 F400 C407 1.14.14.1 0004497,0005506,0005737,0005783,0005789,0006805,0008392,0016020,0016705,0016712,0019373,0020037,0043231,0046872,0070330 ic50=2uM P00178 22909231 504 GKLPPGPSPLPVLGNLLQMDKGLLRSFLRLREKYGDVFTVYLGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGERWRALRRFSLATMRDFMGKRSVEERIQEEARCLVEELRKSKGALLDNTLLFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFELFSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYLLRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPHVTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGALKRNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDIDLTPRESGVGNVPPSYQIRFLARH