3tib A 2.201 BS01 BMA L 1 Q391 V392 R394 Q310 V311 R313 D151 E277 R292 R371 Y406 D70 E196 R211 R290 Y325 3.2.1.18 0004308,0005975,0016020,0016798,0020002,0033644,0044423,0046761,0046872,0052794,0052795,0052796,0055036 Q194T1 22028647 3 VEYRNWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNDTVHDRIPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTRILFIEEGKIVHISPLSGSAQHIEECSCYPRYPGVRCICRDNWKGSNRPVVDINMEDYSIDSSYVCSGLVGDTPRNDDSSSNSNCRNPNNERGTQGVKGWAFDNGNDLWMGRTISKESRSGYETFKVIGGWSTPNSKSQVNRQVIVDNNNWSGYSGIFSVEGKSCINRCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI 3tib A 2.201 BS02 MAN L 1 Q391 R394 Q310 R313 D151 E277 R292 R371 Y406 D70 E196 R211 R290 Y325 3.2.1.18 0004308,0005975,0016020,0016798,0020002,0033644,0044423,0046761,0046872,0052794,0052795,0052796,0055036 Q194T1 22028647 4 VEYRNWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNDTVHDRIPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTRILFIEEGKIVHISPLSGSAQHIEECSCYPRYPGVRCICRDNWKGSNRPVVDINMEDYSIDSSYVCSGLVGDTPRNDDSSSNSNCRNPNNERGTQGVKGWAFDNGNDLWMGRTISKESRSGYETFKVIGGWSTPNSKSQVNRQVIVDNNNWSGYSGIFSVEGKSCINRCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI 3tib A 2.201 BS03 CA A 1 D293 G297 D324 G345 Q347 D212 G216 D243 G264 Q266 D151 E277 R292 R371 Y406 D70 E196 R211 R290 Y325 3.2.1.18 0004308,0005975,0016020,0016798,0020002,0033644,0044423,0046761,0046872,0052794,0052795,0052796,0055036 Q194T1 22028647 501 VEYRNWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNDTVHDRIPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTRILFIEEGKIVHISPLSGSAQHIEECSCYPRYPGVRCICRDNWKGSNRPVVDINMEDYSIDSSYVCSGLVGDTPRNDDSSSNSNCRNPNNERGTQGVKGWAFDNGNDLWMGRTISKESRSGYETFKVIGGWSTPNSKSQVNRQVIVDNNNWSGYSGIFSVEGKSCINRCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI 3tib A 2.201 BS04 LVO A 1 R118 E119 D151 R152 W178 I222 R224 A246 E276 R292 R371 Y406 R37 E38 D70 R71 W97 I141 R143 A165 E195 R211 R290 Y325 D151 E277 R292 R371 Y406 D70 E196 R211 R290 Y325 3.2.1.18 0004308,0005975,0016020,0016798,0020002,0033644,0044423,0046761,0046872,0052794,0052795,0052796,0055036 ic50=129nM -logKd/Ki=6.89, IC50=129nM Q194T1 22028647 801 VEYRNWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNDTVHDRIPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTRILFIEEGKIVHISPLSGSAQHIEECSCYPRYPGVRCICRDNWKGSNRPVVDINMEDYSIDSSYVCSGLVGDTPRNDDSSSNSNCRNPNNERGTQGVKGWAFDNGNDLWMGRTISKESRSGYETFKVIGGWSTPNSKSQVNRQVIVDNNNWSGYSGIFSVEGKSCINRCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI