3s0n A 1.95 BS01 ZN A 1 H10 E64 H10 E64 H45 D89 K179 G180 D181 S182 G183 H45 D89 K179 G180 D181 S182 G183 3.4.21.39 0002003,0004175,0004252,0005576,0005615,0005737,0005829,0006508,0006518,0008236,0016485,0022617,0030141,0030163,0030901,0034769,0036464,0042277,0043231,0045766,0050727,0062023,0071333,0140447 P23946 21733690 229 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQKNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGAAQGIVSYGRSDAKPPAVFTRISHYQPWINQILQAN 3s0n A 1.95 BS02 0BB A 1 H45 L86 A177 F178 K179 S182 S197 Y198 G199 R200 H45 L86 A177 F178 K179 S182 S197 Y198 G199 R200 H45 D89 K179 G180 D181 S182 G183 H45 D89 K179 G180 D181 S182 G183 3.4.21.39 0002003,0004175,0004252,0005576,0005615,0005737,0005829,0006508,0006518,0008236,0016485,0022617,0030141,0030163,0030901,0034769,0036464,0042277,0043231,0045766,0050727,0062023,0071333,0140447 ic50=180nM -logKd/Ki=6.74, IC50=180nM IC50=180nM P23946 21733690 230 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQKNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGAAQGIVSYGRSDAKPPAVFTRISHYQPWINQILQAN