3qvv A 2.35 BS01 A3P A 1 K48 G50 T51 T52 W53 R130 S138 Y193 T227 F229 F255 M256 R257 K258 G259 K41 G43 T44 T45 W46 R123 S131 Y186 T220 F222 F248 M249 R250 K251 G252 K48 H108 S138 K41 H101 S131 2.8.2.1 0004062,0005515,0005737,0005829,0006068,0006584,0006805,0008146,0008202,0008210,0009308,0009812,0016740,0047894,0050294,0050427,0050656,0051923 P50225 21723874 2001 SRQPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIFNRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVHPDPGTWDSFLEKFMVGEVCYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGHSLPEETVDFMVQHTSFKEMKKNPMTNYTTIPQEIMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 3qvv A 2.35 BS02 3QV A 1 F81 F84 K106 H108 V148 I247 F74 F77 K99 H101 V141 I240 K48 H108 S138 K41 H101 S131 2.8.2.1 0004062,0005515,0005737,0005829,0006068,0006584,0006805,0008146,0008202,0008210,0009308,0009812,0016740,0047894,0050294,0050427,0050656,0051923 Ki=38uM -logKd/Ki=4.42, Ki=38uM P50225 21723874 296 SRQPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIFNRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVHPDPGTWDSFLEKFMVGEVCYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGHSLPEETVDFMVQHTSFKEMKKNPMTNYTTIPQEIMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL