3nx7 A 1.8 BS01 ZN A 1 H218 H222 H228 H113 H117 H123 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 17269766 264 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 3nx7 A 1.8 BS02 ZN A 2 H168 D170 H183 H196 H63 D65 H78 H91 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 17269766 265 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 3nx7 A 1.8 BS03 CA A 1 D158 G190 G192 D194 D53 G85 G87 D89 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 17269766 266 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 3nx7 A 1.8 BS04 CA A 2 D124 E199 E201 D19 E94 E96 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 17269766 267 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 3nx7 A 1.8 BS05 CA A 3 D175 G176 G178 I180 D198 E201 D70 G71 G73 I75 D93 E96 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 17269766 268 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 3nx7 A 1.8 BS06 NHK A 1 L181 A182 H218 E219 H222 H228 P238 Y240 L76 A77 H113 E114 H117 H123 P133 Y135 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 Kd=7.88nM -logKd/Ki=8.10, Kd=7.88nM Ki=7.6nM P39900 17269766 0 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG