3mvh A 2.01 BS01 peptide B 0 H194 E234 F236 D274 K276 E278 F309 C310 G311 T312 P313 E314 Y315 E341 H50 E90 F92 D130 K132 E134 F165 C166 G167 T168 P169 E170 Y171 E197 D274 K276 N279 D292 T312 D130 K132 N135 D148 T168 2.7.11.1 0004672,0004674,0005524,0006468 P31749 20481595 1 ~ 10 VTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQRPHFPQFDYSA 3mvh A 2.01 BS02 MN A 1 E314 H354 E170 H210 D274 K276 N279 D292 T312 D130 K132 N135 D148 T168 2.7.11.1 0004672,0004674,0005524,0006468 P31749 20481595 1 VTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQRPHFPQFDYSA 3mvh A 2.01 BS03 WFE A 1 L156 G157 K158 G162 V164 A177 M227 E228 Y229 A230 E234 M281 T291 D292 F438 L12 G13 K14 G18 V20 A33 M83 E84 Y85 A86 E90 M137 T147 D148 F294 D274 K276 N279 D292 T312 D130 K132 N135 D148 T168 2.7.11.1 0004672,0004674,0005524,0006468 ic50=0.5nM -logKd/Ki=9.30, IC50=0.5nM IC50=0.5nM P31749 20481595 999 VTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQRPHFPQFDYSA