3l9l A 2.0 BS01 peptide C 0 L82 Q84 E127 F129 R133 E170 F187 L198 G200 P202 E203 E230 Y235 F239 D241 L72 Q74 E117 F119 R123 E160 F177 L188 G190 P192 E193 E220 Y225 F229 D231 D166 K168 E170 N171 D184 T201 D156 K158 E160 N161 D174 T191 2.7.11.11 0000287,0001669,0001707,0001843,0002027,0003091,0004672,0004674,0004679,0004691,0004712,0005515,0005524,0005634,0005654,0005737,0005739,0005759,0005813,0005829,0005886,0005930,0005952,0006397,0006468,0006611,0007189,0007193,0010737,0010881,0016241,0016310,0016607,0018105,0019221,0019901,0019904,0030145,0031410,0031514,0031594,0031625,0032024,0032703,0034237,0034380,0034605,0034704,0035694,0036126,0044853,0045542,0045667,0045722,0045879,0046827,0048240,0048471,0050804,0050850,0051726,0055117,0061136,0070062,0070417,0070613,0071333,0071374,0071377,0071872,0086064,0097546,0098794,0098978,0099103,0099170,0106310,1903779,1904262,1904539,1990044,2000810 P17612 20137943 5 ~ 23 EQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 3l9l A 2.0 BS02 L9L A 1 F54 V57 A70 K72 Y122 V123 E127 E170 N171 L173 T183 D184 F327 F44 V47 A60 K62 Y112 V113 E117 E160 N161 L163 T173 D174 F317 D166 K168 E170 N171 D184 T201 D156 K158 E160 N161 D174 T191 2.7.11.11 0000287,0001669,0001707,0001843,0002027,0003091,0004672,0004674,0004679,0004691,0004712,0005515,0005524,0005634,0005654,0005737,0005739,0005759,0005813,0005829,0005886,0005930,0005952,0006397,0006468,0006611,0007189,0007193,0010737,0010881,0016241,0016310,0016607,0018105,0019221,0019901,0019904,0030145,0031410,0031514,0031594,0031625,0032024,0032703,0034237,0034380,0034605,0034704,0035694,0036126,0044853,0045542,0045667,0045722,0045879,0046827,0048240,0048471,0050804,0050850,0051726,0055117,0061136,0070062,0070417,0070613,0071333,0071374,0071377,0071872,0086064,0097546,0098794,0098978,0099103,0099170,0106310,1903779,1904262,1904539,1990044,2000810 ic50=167nM -logKd/Ki=6.78, IC50=167nM P17612 20137943 351 EQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF