3iop A 2.2 BS01 8I1 A 1 G89 E90 G91 S94 V96 A109 K111 L159 S160 Y161 A162 G165 E209 L212 T222 D223 G15 E16 G17 S20 V22 A35 K37 L85 S86 Y87 A88 G91 E135 L138 T148 D149 D205 K207 E209 N210 D223 T245 D131 K133 E135 N136 D149 T162 2.7.11.1 0004672,0004674,0005524,0006468 ic50=17nM -logKd/Ki=7.77, IC50=17nM IC50=17nM O15530 20074837 1 RKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLT