3eos A 1.78 BS01 ZN A 1 C318 C320 C323 H349 C291 C293 C296 H322 D102 D280 C318 C320 C323 H349 D92 D258 C291 C293 C296 H322 2.4.2.29 0002099,0005737,0005829,0006400,0008033,0008479,0008616,0016757,0016763,0046872,0101030 P28720 19894214 387 RPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLKQSEEGVTFHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFA 3eos A 1.78 BS02 PK2 A 1 V45 N70 D102 Y106 Q107 D156 C158 G229 G230 A232 M260 G261 D280 V35 N60 D92 Y96 Q97 D134 C136 G207 G208 A210 M238 G239 D258 D102 D280 C318 C320 C323 H349 D92 D258 C291 C293 C296 H322 2.4.2.29 0002099,0005737,0005829,0006400,0008033,0008479,0008616,0016757,0016763,0046872,0101030 Ki=4nM -logKd/Ki=8.40, Ki=4nM P28720 19894214 400 RPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLKQSEEGVTFHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFA