3dzy A 3.1 BS01 dna C 0 K145 H146 Y147 R164 Q206 E208 R209 K14 H15 Y16 R33 Q75 E77 R78 ? 0000122,0000785,0000976,0000977,0000978,0000981,0001221,0001972,0002157,0003677,0003690,0003700,0003707,0004879,0005515,0005634,0005654,0005667,0005737,0005739,0005829,0006355,0008270,0009755,0010875,0019899,0030154,0030501,0032411,0032526,0035357,0042277,0042789,0042802,0042809,0043235,0043401,0043565,0044323,0045893,0045944,0046872,0048384,0050692,0050693,0070564,0070644,0090575,1990837 P19793 19043829 3001 ~ 3020 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 3dzy A 3.1 BS02 dna F 0 E153 G154 F158 R161 R184 N185 Q188 R191 R209 E22 G23 F27 R30 R53 N54 Q57 R60 R78 ? 0000122,0000785,0000976,0000977,0000978,0000981,0001221,0001972,0002157,0003677,0003690,0003700,0003707,0004879,0005515,0005634,0005654,0005667,0005737,0005739,0005829,0006355,0008270,0009755,0010875,0019899,0030154,0030501,0032411,0032526,0035357,0042277,0042789,0042802,0042809,0043235,0043401,0043565,0044323,0045893,0045944,0046872,0048384,0050692,0050693,0070564,0070644,0090575,1990837 P19793 19043829 4001 ~ 4020 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 3dzy A 3.1 BS03 peptide G 0 L294 Q297 V298 R302 T449 F450 E453 L141 Q144 V145 R149 T296 F297 E300 ? 0000122,0000785,0000976,0000977,0000978,0000981,0001221,0001972,0002157,0003677,0003690,0003700,0003707,0004879,0005515,0005634,0005654,0005667,0005737,0005739,0005829,0006355,0008270,0009755,0010875,0019899,0030154,0030501,0032411,0032526,0035357,0042277,0042789,0042802,0042809,0043235,0043401,0043565,0044323,0045893,0045944,0046872,0048384,0050692,0050693,0070564,0070644,0090575,1990837 P19793 19043829 688 ~ 696 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 3dzy A 3.1 BS04 9CR A 1 I268 Q275 F313 R316 A327 C432 I115 Q122 F160 R163 A174 C279 ? 0000122,0000785,0000976,0000977,0000978,0000981,0001221,0001972,0002157,0003677,0003690,0003700,0003707,0004879,0005515,0005634,0005654,0005667,0005737,0005739,0005829,0006355,0008270,0009755,0010875,0019899,0030154,0030501,0032411,0032526,0035357,0042277,0042789,0042802,0042809,0043235,0043401,0043565,0044323,0045893,0045944,0046872,0048384,0050692,0050693,0070564,0070644,0090575,1990837 EC50=100nM, Ki=583nM, IC50=32nM, Kd=240nM P19793 19043829 463 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 3dzy A 3.1 BS05 ZN A 1 C135 C152 C155 C4 C21 C24 ? 0000122,0000785,0000976,0000977,0000978,0000981,0001221,0001972,0002157,0003677,0003690,0003700,0003707,0004879,0005515,0005634,0005654,0005667,0005737,0005739,0005829,0006355,0008270,0009755,0010875,0019899,0030154,0030501,0032411,0032526,0035357,0042277,0042789,0042802,0042809,0043235,0043401,0043565,0044323,0045893,0045944,0046872,0048384,0050692,0050693,0070564,0070644,0090575,1990837 P19793 19043829 7221 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 3dzy A 3.1 BS06 ZN A 2 C171 C177 C187 C190 C40 C46 C56 C59 ? 0000122,0000785,0000976,0000977,0000978,0000981,0001221,0001972,0002157,0003677,0003690,0003700,0003707,0004879,0005515,0005634,0005654,0005667,0005737,0005739,0005829,0006355,0008270,0009755,0010875,0019899,0030154,0030501,0032411,0032526,0035357,0042277,0042789,0042802,0042809,0043235,0043401,0043565,0044323,0045893,0045944,0046872,0048384,0050692,0050693,0070564,0070644,0090575,1990837 P19793 19043829 7222 KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML