2wot A 1.85 BS01 ZZG A 1 I211 A230 K232 L260 L278 S280 Y282 H283 G286 L340 A350 D351 I14 A33 K35 L63 L81 S83 Y85 H86 G89 L143 A153 D154 D333 K335 N338 D351 T375 D136 K138 N141 D154 T178 2.7.11.30 0004672,0004675,0005524,0006468,0007178,0016020 ic50=44nM -logKd/Ki=7.36, IC50=44nM IC50=44nM, EC50=55nM P36897 19736928 1500 GGTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEG