2uw7 A 2.1 BS01 peptide I 0 E127 F129 R133 E170 L198 G200 P202 E203 E230 Y235 P236 F239 A240 D241 D328 Y330 E114 F116 R120 E157 L185 G187 P189 E190 E217 Y222 P223 F226 A227 D228 D315 Y317 D166 K168 E170 N171 D184 T201 D153 K155 E157 N158 D171 T188 2.7.11.11 0001669,0001707,0004672,0004674,0004679,0004691,0005515,0005524,0005634,0005737,0005739,0005829,0005886,0005952,0006468,0010737,0016310,0018105,0019904,0031594,0034237,0034605,0036126,0048471,0106310,1904262 P00517 17451234 5 ~ 24 SVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLTKLEFSFKDNSNLYMVMEYAPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLMIDQQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 2uw7 A 2.1 BS02 GVP A 1 G50 G52 G55 R56 V57 A70 E121 E127 E170 M173 T183 D184 G37 G39 G42 R43 V44 A57 E108 E114 E157 M160 T170 D171 D166 K168 E170 N171 D184 T201 D153 K155 E157 N158 D171 T188 2.7.11.11 0001669,0001707,0004672,0004674,0004679,0004691,0005515,0005524,0005634,0005737,0005739,0005829,0005886,0005952,0006468,0010737,0016310,0018105,0019904,0031594,0034237,0034605,0036126,0048471,0106310,1904262 ic50=18nM -logKd/Ki=7.74, IC50=18nM P00517 17451234 1351 SVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLTKLEFSFKDNSNLYMVMEYAPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLMIDQQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF