2uw3 A 2.19 BS01 peptide I 0 E127 F129 R133 E170 L198 C199 G200 P202 E203 E230 Y235 P236 F239 D241 D328 Y330 E114 F116 R120 E157 L185 C186 G187 P189 E190 E217 Y222 P223 F226 D228 D315 Y317 D166 K168 E170 N171 D184 T201 D153 K155 E157 N158 D171 T188 2.7.11.11 0001669,0001707,0004672,0004674,0004679,0004691,0005515,0005524,0005634,0005737,0005739,0005829,0005886,0005952,0006468,0010737,0016310,0018105,0019904,0031594,0034237,0034605,0036126,0048471,0106310,1904262 P00517 17451234 5 ~ 24 SVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLTKLEFSFKDNSNLYMVMEYAPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLMIDQQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 2uw3 A 2.19 BS02 GVG A 1 L49 V57 A70 M120 Y122 M173 T183 L36 V44 A57 M107 Y109 M160 T170 D166 K168 E170 N171 D184 T201 D153 K155 E157 N158 D171 T188 2.7.11.11 0001669,0001707,0004672,0004674,0004679,0004691,0005515,0005524,0005634,0005737,0005739,0005829,0005886,0005952,0006468,0010737,0016310,0018105,0019904,0031594,0034237,0034605,0036126,0048471,0106310,1904262 ic50=80uM -logKd/Ki=4.10, IC50=80uM P00517 17451234 1351 SVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLTKLEFSFKDNSNLYMVMEYAPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLMIDQQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF