2qwc A 1.6 BS01 CA A 1 D293 N294 G297 D324 N347 D213 N214 G217 D244 N266 D151 E277 K292 R371 Y406 D70 E197 K212 R290 Y324 3.2.1.18 0004308,0005975,0016020,0033644,0046761,0055036 P03472 9655825 999 RDFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSCHDGKTRMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCHNGVCPVVFTDGSATGPAETRIYYFKEGKILKWEPLAGTAKHIEECSCYGERAEITCTCKDNWQGSNRPVIRIDPVAMTHTSQYICSPVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGVNTWLGRTISIASRSGYEMLKVPNALTDDKSKPTQGQTIVLNTDWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWDWPDGAKIEYFL 2qwc A 1.6 BS02 DAN A 1 R118 E119 D151 R152 W178 A246 E276 K292 R371 Y406 R37 E38 D70 R71 W98 A166 E196 K212 R290 Y324 D151 E277 K292 R371 Y406 D70 E197 K212 R290 Y324 3.2.1.18 0004308,0005975,0016020,0033644,0046761,0055036 Ki=280uM -logKd/Ki=3.55, Ki=280uM IC50=13000nM P03472 9655825 800 RDFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSCHDGKTRMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCHNGVCPVVFTDGSATGPAETRIYYFKEGKILKWEPLAGTAKHIEECSCYGERAEITCTCKDNWQGSNRPVIRIDPVAMTHTSQYICSPVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGVNTWLGRTISIASRSGYEMLKVPNALTDDKSKPTQGQTIVLNTDWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWDWPDGAKIEYFL