2pjt A 2.8 BS01 ZN A 1 H197 H201 H207 H119 H123 H129 H197 E198 H201 H207 H119 E120 H123 H129 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 17606376 302 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTHFMLPDDDVQGIQSLYGP 2pjt A 2.8 BS02 ZN A 2 H147 D149 H162 H175 H69 D71 H84 H97 H197 E198 H201 H207 H119 E120 H123 H129 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 17606376 303 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTHFMLPDDDVQGIQSLYGP 2pjt A 2.8 BS03 CA A 1 D154 G155 S157 L159 D177 E180 D76 G77 S79 L81 D99 E102 H197 E198 H201 H207 H119 E120 H123 H129 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 17606376 304 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTHFMLPDDDVQGIQSLYGP 2pjt A 2.8 BS04 CA A 2 D137 N169 G171 D173 D59 N91 G93 D95 H197 E198 H201 H207 H119 E120 H123 H129 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 17606376 305 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTHFMLPDDDVQGIQSLYGP 2pjt A 2.8 BS05 CA A 3 T105 H106 T27 H28 H197 E198 H201 H207 H119 E120 H123 H129 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 17606376 307 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTHFMLPDDDVQGIQSLYGP 2pjt A 2.8 BS06 347 A 1 L159 L160 A161 H197 E198 H201 H207 L214 P217 Y219 L81 L82 A83 H119 E120 H123 H129 L136 P139 Y141 H197 E198 H201 H207 H119 E120 H123 H129 3.4.24.- 0004222,0006508,0008237,0008270,0031012 -logKd/Ki=6.07, IC50=860nM IC50=860nM P45452 17606376 401 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTHFMLPDDDVQGIQSLYGP