2pdw A 1.55 BS01 NAP A 1 G18 T19 W20 D43 Y48 H110 N160 Q183 Y209 S210 P211 L212 S214 P215 D216 A245 I260 P261 K262 S263 T265 R268 E271 N272 C298 G18 T19 W20 D43 Y48 H110 N160 Q183 Y209 S210 P211 L212 S214 P215 D216 A245 I260 P261 K262 S263 T265 R268 E271 N272 C298 D43 Y48 K77 H110 D43 Y48 K77 H110 1.1.1.21,1.1.1.300,1.1.1.372,1.1.1.54 0001523,0001758,0002070,0003091,0004032,0005515,0005615,0005654,0005737,0005739,0005829,0005975,0006629,0006693,0006700,0009055,0016491,0019853,0035809,0036130,0042572,0043066,0043795,0044597,0044598,0046370,0047655,0047939,0047956,0052650,0070062,0071475,0072205 P15121 18495158 500 ASRILLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSDTSHKDYPFHEEF 2pdw A 1.55 BS02 FID A 1 W20 Y48 H110 W111 C298 L300 W20 Y48 H110 W111 C298 L300 D43 Y48 K77 H110 D43 Y48 K77 H110 1.1.1.21,1.1.1.300,1.1.1.372,1.1.1.54 0001523,0001758,0002070,0003091,0004032,0005515,0005615,0005654,0005737,0005739,0005829,0005975,0006629,0006693,0006700,0009055,0016491,0019853,0035809,0036130,0042572,0043066,0043795,0044597,0044598,0046370,0047655,0047939,0047956,0052650,0070062,0071475,0072205 Kd=37nM IC50=35nM, Kd=16nM P15121 18495158 600 ASRILLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALLSDTSHKDYPFHEEF