2ow1 A 2.2 BS01 ZN A 1 H401 H405 H411 H117 H121 H127 H401 Q402 H405 H411 H117 Q118 H121 H127 3.4.24.35 0004222,0006508,0008237,0008270,0031012 P14780 17599356 444 FEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHQFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLY 2ow1 A 2.2 BS02 ZN A 2 H175 D177 H190 H203 H66 D68 H81 H94 H401 Q402 H405 H411 H117 Q118 H121 H127 3.4.24.35 0004222,0006508,0008237,0008270,0031012 P14780 17599356 445 FEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHQFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLY 2ow1 A 2.2 BS03 CA A 1 D182 G183 D185 L187 D205 E208 D73 G74 D76 L78 D96 E99 H401 Q402 H405 H411 H117 Q118 H121 H127 3.4.24.35 0004222,0006508,0008237,0008270,0031012 P14780 17599356 446 FEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHQFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLY 2ow1 A 2.2 BS04 CA A 2 D165 G197 Q199 D201 D56 G88 Q90 D92 H401 Q402 H405 H411 H117 Q118 H121 H127 3.4.24.35 0004222,0006508,0008237,0008270,0031012 P14780 17599356 447 FEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHQFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLY 2ow1 A 2.2 BS05 CA A 3 D131 D206 E208 D22 D97 E99 H401 Q402 H405 H411 H117 Q118 H121 H127 3.4.24.35 0004222,0006508,0008237,0008270,0031012 P14780 17599356 448 FEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHQFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLY 2ow1 A 2.2 BS06 CA A 4 S149 T152 S40 T43 H401 Q402 H405 H411 H117 Q118 H121 H127 3.4.24.35 0004222,0006508,0008237,0008270,0031012 P14780 17599356 449 FEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHQFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLY 2ow1 A 2.2 BS07 7MR A 1 L188 A189 H401 Q402 H405 H411 L418 P421 M422 Y423 R424 L79 A80 H117 Q118 H121 H127 L134 P137 M138 Y139 R140 H401 Q402 H405 H411 H117 Q118 H121 H127 3.4.24.35 0004222,0006508,0008237,0008270,0031012 -logKd/Ki=9.00, IC50=1nM P14780 17599356 501 FEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHQFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLY