2ipw A 2.0 BS01 NAP A 1 G18 T19 W20 K21 D43 Y48 H110 Q183 Y209 S210 P211 L212 S214 P215 D216 A245 I260 P261 K262 S263 V264 T265 R268 E271 N272 G17 T18 W19 K20 D42 Y47 H109 Q179 Y205 S206 P207 L208 S210 P211 D212 A239 I254 P255 K256 S257 V258 T259 R262 E265 N266 D43 Y48 K77 H110 D42 Y47 K76 H109 1.1.1.21,1.1.1.300,1.1.1.372,1.1.1.54 0001523,0001758,0002070,0003091,0004032,0005515,0005615,0005654,0005737,0005739,0005829,0005975,0006629,0006693,0006700,0009055,0016491,0019853,0035809,0036130,0042572,0043066,0043795,0044597,0044598,0046370,0047655,0047939,0047956,0052650,0070062,0071475,0072205 P15121 17083960 316 SRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPYAEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVAALLSCTSHKDYPFHEEF 2ipw A 2.0 BS02 2CL A 1 W20 Y48 H110 W19 Y47 H109 D43 Y48 K77 H110 D42 Y47 K76 H109 1.1.1.21,1.1.1.300,1.1.1.372,1.1.1.54 0001523,0001758,0002070,0003091,0004032,0005515,0005615,0005654,0005737,0005739,0005829,0005975,0006629,0006693,0006700,0009055,0016491,0019853,0035809,0036130,0042572,0043066,0043795,0044597,0044598,0046370,0047655,0047939,0047956,0052650,0070062,0071475,0072205 Ki=1uM Ki=4400nM, IC50=4400nM P15121 17083960 317 SRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPYAEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVAALLSCTSHKDYPFHEEF