2h8h A 2.2 BS01 H8H A 1 L273 V281 A293 K295 T338 Y340 M341 S342 G344 L393 D404 L189 V197 A209 K211 T254 Y256 M257 S258 G260 L309 D320 D386 R388 A390 N391 D404 F424 D302 R304 A306 N307 D320 F340 2.7.10.2 0000122,0001545,0001819,0002102,0002223,0002376,0002862,0004672,0004713,0004715,0005080,0005102,0005158,0005178,0005515,0005524,0005634,0005654,0005737,0005739,0005743,0005764,0005770,0005829,0005856,0005884,0005886,0005901,0005925,0006468,0007155,0007165,0007172,0007173,0007179,0007229,0007283,0007611,0008284,0009410,0009612,0010447,0010628,0010629,0010632,0010634,0010907,0010954,0014856,0014911,0016004,0016020,0016236,0016301,0016310,0016477,0018108,0019899,0019901,0019904,0020037,0022407,0030054,0030154,0030168,0030331,0030900,0031295,0031333,0031648,0031667,0032205,0032587,0032869,0033146,0033625,0034139,0034332,0034446,0034614,0035306,0035331,0035556,0036035,0036120,0038083,0038096,0038128,0038166,0042169,0042476,0042542,0043025,0043065,0043066,0043114,0043149,0043154,0043274,0044294,0044325,0044877,0045056,0045087,0045121,0045124,0045296,0045453,0045747,0045780,0045785,0045821,0046579,0046628,0046718,0046777,0046875,0048008,0048010,0048011,0048013,0048041,0048471,0048477,0050731,0050839,0050847,0050900,0051057,0051117,0051219,0051222,0051385,0051450,0051602,0051895,0051897,0051902,0060065,0060444,0060491,0060576,0070062,0070102,0070161,0070301,0070374,0070542,0070555,0070700,0071222,0071253,0071375,0071393,0071398,0071456,0071498,0071560,0071803,0071897,0071902,0086091,0090263,0097060,0097110,0098609,0098978,0099091,1900182,1902533,1902737,1903997,1904263,1904385,1904707,1990646,2000256,2000386,2000394,2000588,2000641,2000811,2001237,2001243,2001286 ic50=2.7nM -logKd/Ki=8.57, IC50=2.7nM IC50=2.7nM P12931 17064066 534 TFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQP