2bxr A 3.0 BS01 FAD A 1 I19 G20 G22 S24 L42 E43 A44 R45 G50 R51 G66 G67 A68 Y69 P243 V244 I273 W397 Y402 C406 Y407 G434 T435 G443 Y444 M445 A448 I8 G9 G11 S13 L31 E32 A33 R34 G39 R40 G55 G56 A57 Y58 P224 V225 I254 W378 Y383 C387 Y388 G415 T416 G424 Y425 M426 A429 G71 R206 K305 G60 R190 K286 1.4.3.21,1.4.3.4 0005515,0005739,0005741,0005829,0006576,0006584,0008131,0009967,0016491,0042420,0050660,0052595,0097621 P21397 16129825 600 HMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLG 2bxr A 3.0 BS02 MLG A 1 I335 L337 F352 Y407 I316 L318 F333 Y388 G71 R206 K305 G60 R190 K286 1.4.3.21,1.4.3.4 0005515,0005739,0005741,0005829,0006576,0006584,0008131,0009967,0016491,0042420,0050660,0052595,0097621 IC50=4.5nM, Ki=12nM P21397 16129825 601 HMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLG