1ztq A 2.0 BS01 ZN A 1 H197 H201 H207 H116 H120 H126 H197 E198 H201 H207 H116 E117 H120 H126 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 16005220 550 YNVFLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGP 1ztq A 2.0 BS02 ZN A 2 H147 D149 H162 H175 H66 D68 H81 H94 H197 E198 H201 H207 H116 E117 H120 H126 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 16005220 551 YNVFLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGP 1ztq A 2.0 BS03 CA A 1 D154 G155 S157 L159 D177 E180 D73 G74 S76 L78 D96 E99 H197 E198 H201 H207 H116 E117 H120 H126 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 16005220 560 YNVFLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGP 1ztq A 2.0 BS04 CA A 2 D137 N169 G171 D173 D56 N88 G90 D92 H197 E198 H201 H207 H116 E117 H120 H126 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 16005220 561 YNVFLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGP 1ztq A 2.0 BS05 CA A 3 D103 D178 E180 D22 D97 E99 H197 E198 H201 H207 H116 E117 H120 H126 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 16005220 562 YNVFLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGP 1ztq A 2.0 BS06 033 A 1 L159 L160 A161 H197 E198 H201 H207 G212 L214 F216 P217 I218 Y219 T220 F227 P230 L78 L79 A80 H116 E117 H120 H126 G131 L133 F135 P136 I137 Y138 T139 F146 P149 H197 E198 H201 H207 H116 E117 H120 H126 3.4.24.- 0004222,0006508,0008237,0008270,0031012 ic50=1.3nM -logKd/Ki=8.89, IC50=1.3nM IC50=1.3nM P45452 16005220 601 YNVFLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGP