1zgi A 2.2 BS01 peptide B 0 F34 Q38 L40 R67 R73 T74 R75 Y76 K81 I82 F45 Q50 L52 R88 R94 T95 R96 Y97 K103 I104 H57 D102 E192 G193 D194 S195 G196 H69 D125 E220 G221 D222 S223 G224 3.4.21.5 0004252,0005509,0005576,0006508,0007596 P00734 16137886 355 ~ 364 DCGLRPLFEKKSLEDKTERELLESYIIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG 1zgi A 2.2 BS02 382 A 1 H57 Y60A W60D E97A N98 L99 A190 E192 S195 V213 W215 G216 G219 C220 H69 Y73 W76 E120 N121 L122 A218 E220 S223 V243 W245 G246 G248 C249 H57 D102 E192 G193 D194 S195 G196 H69 D125 E220 G221 D222 S223 G224 3.4.21.5 0004252,0005509,0005576,0006508,0007596 Ki=4.6uM -logKd/Ki=5.34, Ki=4.6uM Ki=4.6nM P00734 16137886 1001 DCGLRPLFEKKSLEDKTERELLESYIIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKEGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFG