1uou A 2.11 BS01 CMU A 1 H116 S117 T118 L148 Y199 R202 I214 S217 K221 H84 S85 T86 L116 Y167 R170 I182 S185 K189 D114 K115 H116 S117 T154 D195 R202 S217 K221 K222 D82 K83 H84 S85 T122 D163 R170 S185 K189 K190 2.4.2.4 0000002,0001525,0004645,0005515,0005829,0006206,0006213,0006935,0007165,0008083,0009032,0016154,0016757,0016763,0030154,0031641,0042803,0046074,0051969,1905333 Ki=20nM -logKd/Ki=7.70, Ki=20nM IC50=35nM, Ki=20nM P19971 14725767 1481 PKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRALPLALVLHELGALRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAPLPFAELVLPP