1r1j A 2.35 BS01 ZN A 1 H583 H587 E646 H530 H534 E593 H583 E584 H587 E646 D650 H711 R717 H530 E531 H534 E593 D597 H658 R664 3.4.24.11 0001786,0001822,0001890,0004175,0004222,0005515,0005737,0005769,0005802,0005886,0005903,0005925,0006508,0006518,0007611,0008021,0008233,0008237,0008238,0008270,0009986,0010814,0010815,0016020,0016485,0019233,0030163,0030324,0030424,0030425,0030667,0031410,0042277,0042447,0042803,0043025,0043627,0044306,0045121,0045202,0046449,0046872,0050435,0050769,0061837,0070012,0070062,0071345,0071492,0071493,0090399,0097242,0098793,0150094,1900273,1901612 P08473 14747736 1001 GICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 1r1j A 2.35 BS02 OIR A 1 F106 N542 A543 F544 M579 V580 H583 E584 H587 E646 W693 H711 R717 F53 N489 A490 F491 M526 V527 H530 E531 H534 E593 W640 H658 R664 H583 E584 H587 E646 D650 H711 R717 H530 E531 H534 E593 D597 H658 R664 3.4.24.11 0001786,0001822,0001890,0004175,0004222,0005515,0005737,0005769,0005802,0005886,0005903,0005925,0006508,0006518,0007611,0008021,0008233,0008237,0008238,0008270,0009986,0010814,0010815,0016020,0016485,0019233,0030163,0030324,0030424,0030425,0030667,0031410,0042277,0042447,0042803,0043025,0043627,0044306,0045121,0045202,0046449,0046872,0050435,0050769,0061837,0070012,0070062,0071345,0071492,0071493,0090399,0097242,0098793,0150094,1900273,1901612 Ki=2.3nM -logKd/Ki=8.64, Ki=2.3nM P08473 14747736 2001 GICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW