1pmv A 2.5 BS01 537 A 1 I70 A91 M146 L148 M149 D150 A151 V196 L206 I26 A47 M102 L104 M105 D106 A107 V152 L162 D189 K191 N194 D207 T226 D145 K147 N150 D163 T177 2.7.11.24 0004672,0004707,0005524,0006468 ic50=150nM -logKd/Ki=6.82, IC50=150nM IC50=190nM, Kd=22nM P53779 12954329 501 DNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLASFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQQLDEREHTIEEWKELIYKEVMN