1csi A 1.7 BS01 OAA A 1 H238 N242 H274 H320 R329 R401 H236 N240 H272 H318 R327 R399 S244 H274 H320 R329 D375 S242 H272 H318 R327 D373 2.3.3.1 0004108,0005739,0005759,0005975,0006099,0006101,0016740,0036440,0042802,0046912 P23007 8011640 702 STNLKDVLASLIPKEQARIKTFRQQHGNTAVGQITVDMSYGGMRGMKGLIYETSVLDPDEGIRFRGFSIPECQKLLPKAGGGEEPLPEGLFWLLVTGQIPTPEQVSWVSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGINRTKYWEFVYEDAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDPQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLLWLSQLQKDLGADASDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPSDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTAGLEKLSAGG 1csi A 1.7 BS02 CMX A 1 R46 L273 H274 A277 V314 V315 G317 Y318 G319 H320 A321 K366 A367 K368 N373 D375 R44 L271 H272 A275 V312 V313 G315 Y316 G317 H318 A319 K364 A365 K366 N371 D373 S244 H274 H320 R329 D375 S242 H272 H318 R327 D373 2.3.3.1 0004108,0005739,0005759,0005975,0006099,0006101,0016740,0036440,0042802,0046912 Ki=1.6nM -logKd/Ki=8.80, Ki=1.6nM P23007 8011640 700 STNLKDVLASLIPKEQARIKTFRQQHGNTAVGQITVDMSYGGMRGMKGLIYETSVLDPDEGIRFRGFSIPECQKLLPKAGGGEEPLPEGLFWLLVTGQIPTPEQVSWVSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGINRTKYWEFVYEDAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDPQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLLWLSQLQKDLGADASDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPSDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTAGLEKLSAGG