1b9v A 2.35 BS01 CA A 1 D293 T297 D324 G346 D217 T221 D248 G270 D149 E276 R292 R374 Y409 D73 E200 R216 R298 Y333 3.2.1.18 0004308,0005975,0016020,0033644,0055036 P03474 10547289 500 EPEWTYPRLSCQGSTFQKALLISPHRFGEIKGNSAPLIIREPFVACGPKECRHFALTHYAAQPGGYYNGTRKDRNKLRHLVSVKLGKIPTVENSIFHMAAWSGSACHDGREWTYIGVDGPDNDALVKIKYGEAYTDTYHSYAHNILRTQESACNCIGGDCYLMITDGSASGISKCRFLKIREGRIIKEILPTGRVEHTEECTCGFASNKTIECACRDNSYTAKRPFVKLNVETDTAEIRLMCTKTYLDTPRPDDGSIAGPCESNGDKWLGGIKGGFVHQRMASKIGRWYSRTMSKTNRMGMELYVRYDGDPWTDSDALTLSGVMVSIEEPGWYSFGFEIKDKKCDVPCIGIEMVHDGGKDTWHSAATAIYCLMGSGQLLWDTVTGVDMAL 1b9v A 2.35 BS02 RA2 A 1 R116 E117 D149 R150 W177 R223 E226 E275 E276 R292 N294 R374 Y409 R40 E41 D73 R74 W101 R147 E150 E199 E200 R216 N218 R298 Y333 D149 E276 R292 R374 Y409 D73 E200 R216 R298 Y333 3.2.1.18 0004308,0005975,0016020,0033644,0055036 ic50=224uM -logKd/Ki=3.65, IC50=224uM IC50=271000nM P03474 10547289 468 EPEWTYPRLSCQGSTFQKALLISPHRFGEIKGNSAPLIIREPFVACGPKECRHFALTHYAAQPGGYYNGTRKDRNKLRHLVSVKLGKIPTVENSIFHMAAWSGSACHDGREWTYIGVDGPDNDALVKIKYGEAYTDTYHSYAHNILRTQESACNCIGGDCYLMITDGSASGISKCRFLKIREGRIIKEILPTGRVEHTEECTCGFASNKTIECACRDNSYTAKRPFVKLNVETDTAEIRLMCTKTYLDTPRPDDGSIAGPCESNGDKWLGGIKGGFVHQRMASKIGRWYSRTMSKTNRMGMELYVRYDGDPWTDSDALTLSGVMVSIEEPGWYSFGFEIKDKKCDVPCIGIEMVHDGGKDTWHSAATAIYCLMGSGQLLWDTVTGVDMAL