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●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 24809 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    12801 4eb9:A (2.6) BS02 0O6 2.3.2.27 N/A Q13490 23166698 PDBbind: -logKd/Ki=8.27, IC50=5.4nM
    BindingDB: IC50=5.4nM
    12802 4eb9:C (2.6) BS02 0O6 2.3.2.27 N/A Q13490 23166698 PDBbind: -logKd/Ki=8.27, IC50=5.4nM
    BindingDB: IC50=5.4nM
    12803 4ebv:A (1.67) BS01 0O7 2.7.10.2 GO:0004672 ... Q05397 22819505 MOAD: ic50=0.99uM
    PDBbind: -logKd/Ki=5.38, IC50=4.2uM
    BindingDB: IC50=4200nM
    12804 4ebw:A (2.65) BS01 0PF 2.7.10.2 GO:0004672 ... Q05397 22819505 PDBbind: -logKd/Ki=5.06, IC50=8.7uM
    BindingDB: IC50=>30000nM
    12805 4ec0:A (1.85) BS02 7PQ 2.5.1.18
    5.3.99.2    		 GO:0000287 ... O60760 22546671 PDBbind: -logKd/Ki=6.07, IC50=845nM
    BindingDB: IC50=845nM
    12806 4ec4:A (3.3) BS02 0O6 2.3.2.27 N/A P98170 23166698 PDBbind: -logKd/Ki=7.60, IC50=25.4nM
    BindingDB: IC50=25.4nM
    12807 4ec4:F (3.3) BS01 0O6 2.3.2.27 N/A P98170 23166698 PDBbind: -logKd/Ki=7.60, IC50=25.4nM
    BindingDB: IC50=25.4nM
    12808 4ed5:A (2.0) BS01 rna ? GO:0003676 ... Q15717 23519412 PDBbind: Kd=169nM
    12809 4ed5:B (2.0) BS01 rna ? GO:0003676 ... Q15717 23519412 PDBbind: Kd=169nM
    12810 4ede:B (1.4) BS01 RET ? GO:0005501 ... P50120 23224553 PDBbind: -logKd/Ki=7.38, Kd=42nM
    12811 4edy:A (1.72) BS02 9PQ 2.5.1.18
    5.3.99.2    		 GO:0000287 ... O60760 22546671 PDBbind: -logKd/Ki=5.83, IC50=1480nM
    BindingDB: IC50=1480nM
    12812 4edz:A (2.0) BS02 0O5 2.5.1.18
    5.3.99.2    		 GO:0000287 ... O60760 22546671 PDBbind: -logKd/Ki=8.08, IC50=8.26nM
    BindingDB: IC50=8.26nM
    12813 4ee0:A (1.75) BS01 0O4 2.5.1.18
    5.3.99.2    		 GO:0000287 ... O60760 22546671 PDBbind: -logKd/Ki=8.63, IC50=2.34nM
    BindingDB: IC50=2.34nM
    12814 4eeh:A (1.6) BS01 HH6 3.6.4.10 GO:0005524 ... P07900 22632933 MOAD: ic50=45uM
    PDBbind: -logKd/Ki=4.35, IC50=45uM
    12815 4eej:A (1.501) BS01 RET ? GO:0005501 ... P50120 23224553 PDBbind: -logKd/Ki=7.15, Kd=70nM
    12816 4eev:A (1.8) BS01 L1X 2.7.10.1 GO:0004672 ... P08581 23275061 MOAD: ic50=4.7nM
    PDBbind: -logKd/Ki=8.33, IC50=4.7nM
    BindingDB: IC50=4.7nM
    12817 4ef4:A (2.147) BS01 C2E ? GO:0002218 ... Q86WV6 22579474 Manual survey: Kd=4.42uM (22579474)
    MOAD: Kd=4.42uM
    PDBbind: -logKd/Ki=5.35, Kd=4.42uM
    BindingDB: EC50=4500nM, Kd=1210nM
    12818 4ef4:B (2.147) BS01 C2E ? GO:0002218 ... Q86WV6 22579474 Manual survey: Kd=4.42uM (22579474)
    PDBbind: -logKd/Ki=5.35, Kd=4.42uM
    BindingDB: EC50=4500nM, Kd=1210nM
    12819 4ef6:A (1.94) BS01 I2E 6.3.2.1 GO:0000287 ... P9WIL5 23872845 MOAD: Kd=1.18mM
    PDBbind: -logKd/Ki=2.92, Kd=1.2mM
    12820 4efg:A (1.58) BS01 RET ? GO:0005501 ... P50120 23224553 PDBbind: -logKd/Ki=7.26, Kd=55nM
    12821 4efk:A (1.7) BS01 0OC 6.3.2.1 GO:0000287 ... P9WIL5 23872845 MOAD: Kd=3.18mM
    PDBbind: -logKd/Ki=2.49, Kd=3.2mM
    12822 4efs:A (1.63) BS06 E37 3.4.24.65 GO:0004222 ... P39900 22689580 MOAD: Ki=2.5nM
    PDBbind: -logKd/Ki=8.60, Ki=2.5nM
    BindingDB: Ki=2.5nM
    12823 4eft:A (2.12) BS01 EFT 3.6.4.10 GO:0005524 ... P07900 22632933 MOAD: ic50=85uM
    PDBbind: -logKd/Ki=4.07, IC50=85uM
    12824 4efu:A (2.0) BS01 EFU 3.6.4.10 GO:0005524 ... P07900 22632933 MOAD: ic50=0.25uM
    PDBbind: -logKd/Ki=6.60, IC50=0.25uM
    12825 4egh:A (1.6) BS01 0OY 3.6.4.10 GO:0005524 ... P07900 22573733 MOAD: ic50=550uM
    PDBbind: -logKd/Ki=3.26, IC50=550uM
    12826 4egi:A (1.79) BS01 B2J 3.6.4.10 GO:0005524 ... P07900 22573733 MOAD: ic50=150uM
    PDBbind: -logKd/Ki=3.82, IC50=150uM
    BindingDB: Kd=42000nM
    12827 4egk:A (1.69) BS01 RDC 3.6.4.10 GO:0005524 ... P07900 22573733 MOAD: Kd=19nM
    PDBbind: -logKd/Ki=7.72, Kd=19nM
    BindingDB: Kd=1.2nM
    12828 4egy:A (2.301) BS01 dna ? GO:0003700 ... P96711 23109551 PDBbind: Kd=250nM
    12829 4egy:A (2.301) BS02 dna ? GO:0003700 ... P96711 23109551 PDBbind: Kd=250nM
    12830 4egy:B (2.301) BS01 dna ? GO:0003700 ... P96711 23109551 PDBbind: Kd=250nM
    12831 4egy:B (2.301) BS02 dna ? GO:0003700 ... P96711 23109551 PDBbind: Kd=250nM
    12832 4eh2:A (2.0) BS02 0OK 2.7.11.24 GO:0000077 ... Q16539 23247173 PDBbind: -logKd/Ki=3.16, IC50=692uM
    12833 4eh3:A (2.4) BS01 NAR 2.7.11.24 GO:0000077 ... Q16539 23247173 PDBbind: -logKd/Ki=3.53, IC50=292uM
    12834 4eh4:A (2.5) BS02 0OL 2.7.11.24 GO:0000077 ... Q16539 23247173 PDBbind: -logKd/Ki=2.81, IC50=1534uM
    12835 4eh5:A (2.0) BS02 0OM 2.7.11.24 GO:0000077 ... Q16539 23247173 PDBbind: -logKd/Ki=3.09, IC50=818uM
    12836 4eh6:A (2.1) BS02 0ON 2.7.11.24 GO:0000077 ... Q16539 23247173 PDBbind: -logKd/Ki=2.46, IC50=3471uM
    12837 4eh7:A (2.1) BS02 0OO 2.7.11.24 GO:0000077 ... Q16539 23247173 PDBbind: -logKd/Ki=3.28, IC50=520uM
    12838 4eh8:A (2.2) BS02 0OP 2.7.11.24 GO:0000077 ... Q16539 23247173 PDBbind: -logKd/Ki=2.20, IC50=6247uM
    12839 4eh8:A (2.2) BS03 0OP 2.7.11.24 GO:0000077 ... Q16539 23247173 PDBbind: -logKd/Ki=2.20, IC50=6247uM
    12840 4eh9:A (2.1) BS02 0OQ 2.7.11.24 GO:0000077 ... Q16539 23247173 PDBbind: -logKd/Ki=2.26, IC50=5453uM
    12841 4ehe:A (3.3) BS01 RI8 2.7.11.1 GO:0004672 ... P15056 22335519 PDBbind: -logKd/Ki=8.49, IC50=3.2nM
    12842 4ehe:B (3.3) BS01 RI8 2.7.11.1 GO:0004672 ... P15056 22335519 PDBbind: -logKd/Ki=8.49, IC50=3.2nM
    12843 4ehg:A (3.5) BS01 RI9 2.7.11.1 GO:0004672 ... P15056 22335519 PDBbind: -logKd/Ki=7.19, IC50=64nM
    12844 4ehg:B (3.5) BS01 RI9 2.7.11.1 GO:0004672 ... P15056 22335519 PDBbind: -logKd/Ki=7.19, IC50=64nM
    12845 4ehm:B (2.2) BS01 PJA 2.5.1.60 GO:0003824 ... Q08603 22480322 PDBbind: -logKd/Ki=5.85, IC50=1.4uM
    12846 4ehr:A (2.09) BS01 0Q5 ? GO:0042981 ... Q07817 22608393 MOAD: ic50=0.013uM
    PDBbind: -logKd/Ki=7.89, IC50=13nM
    BindingDB: IC50=13nM
    12847 4ehv:A (1.6) BS01 0SJ 2.7.11.24 GO:0000077 ... Q16539 23247173 PDBbind: -logKd/Ki=2.29, IC50=5103uM
    12848 4ehv:A (1.6) BS02 0SJ 2.7.11.24 GO:0000077 ... Q16539 23247173 PDBbind: -logKd/Ki=2.29, IC50=5103uM
    12849 4ehv:A (1.6) BS04 0SJ 2.7.11.24 GO:0000077 ... Q16539 23247173 PDBbind: -logKd/Ki=2.29, IC50=5103uM
    12850 4ehz:A (2.174) BS01 JAK 2.7.10.2 GO:0004672 ... P23458 22698084 MOAD: Ki=10nM
    PDBbind: -logKd/Ki=8.00, Ki=10nM
    BindingDB: EC50=250nM, Ki=10.0nM
    12851 4ei4:A (2.22) BS01 0Q2 2.7.10.2 GO:0004672 ... P23458 22698084 MOAD: Ki=1.8nM
    PDBbind: -logKd/Ki=8.74, Ki=1.8nM
    12852 4ej2:A (2.65) BS01 D1F 2.4.1.1 GO:0000166 ... P00489 22770609 PDBbind: -logKd/Ki=2.49, Ki=3204uM
    BindingDB: IC50=6100000nM
    12853 4ej8:A (2.347) BS01 1F1 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P12499 23540839 MOAD: Kd=4.1uM
    PDBbind: -logKd/Ki=5.39, Kd=4.1uM
    12854 4ejl:A (2.445) BS01 IOP 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P12499 23540839 MOAD: Kd=7.2uM
    PDBbind: -logKd/Ki=5.14, Kd=7.2uM
    12855 4ejn:A (2.19) BS01 0R4 2.7.11.1 GO:0001649 ... P31749 22533986 MOAD: ic50=0.005uM
    PDBbind: -logKd/Ki=8.30, IC50=5nM
    BindingDB: IC50=44nM
    12856 4ejy:A (2.0) BS01 dna 4.2.99.18 GO:0003684 ... Q8R5T9 23246782 PDBbind: Kd=0.86nM
    12857 4ejy:A (2.0) BS02 dna 4.2.99.18 GO:0003684 ... Q8R5T9 23246782 PDBbind: Kd=0.86nM
    12858 4ejy:B (2.0) BS01 dna 4.2.99.18 GO:0003684 ... Q8R5T9 23246782 PDBbind: Kd=0.86nM
    12859 4ejy:B (2.0) BS02 dna 4.2.99.18 GO:0003684 ... Q8R5T9 23246782 PDBbind: Kd=0.86nM
    12860 4ejz:A (3.05) BS01 dna 4.2.99.18 GO:0003684 ... Q8R5T9 23246782 PDBbind: Kd=8.2nM
    12861 4ejz:A (3.05) BS02 dna 4.2.99.18 GO:0003684 ... Q8R5T9 23246782 PDBbind: Kd=8.2nM
    12862 4ejz:B (3.05) BS01 dna 4.2.99.18 GO:0003684 ... Q8R5T9 23246782 PDBbind: Kd=8.2nM
    12863 4ejz:B (3.05) BS02 dna 4.2.99.18 GO:0003684 ... Q8R5T9 23246782 PDBbind: Kd=8.2nM
    12864 4ek9:A (2.5) BS01 EP4 2.1.1.360 GO:0031151 ... Q8TEK3 22978415 MOAD: Ki=38000nM
    PDBbind: -logKd/Ki=4.42, Ki=38000nM
    BindingDB: Ki=9000nM
    12865 4eke:A (2.6) BS01 D1I 2.4.1.1 GO:0000166 ... P00489 22770609 PDBbind: -logKd/Ki=4.48, Ki=33.4uM
    BindingDB: Ki=33400nM
    12866 4ekg:A (2.8) BS01 0QJ 2.1.1.360 GO:0031151 ... Q8TEK3 22978415 PDBbind: -logKd/Ki=8.77, Kd=1.7nM
    BindingDB: Ki=13nM
    12867 4eki:A (2.85) BS01 0QK 2.1.1.360 GO:0031151 ... Q8TEK3 22978415 PDBbind: -logKd/Ki=10.00, Kd=0.10nM
    BindingDB: Ki=0.300000nM, IC50=0.400000nM, EC50=9.0nM, Kd=0.250000nM
    12868 4eky:A (2.45) BS01 D1J 2.4.1.1 GO:0000166 ... P00489 22770609 MOAD: Ki=303uM
    PDBbind: -logKd/Ki=3.52, Ki=303.0uM
    BindingDB: Ki=303000nM
    12869 4el0:A (2.4) BS01 D1K 2.4.1.1 GO:0000166 ... P00489 22770609 MOAD: Ki=32.4uM
    PDBbind: -logKd/Ki=4.49, Ki=32.4uM
    BindingDB: Ki=32400nM
    12870 4el5:A (2.0) BS01 D1M 2.4.1.1 GO:0000166 ... P00489 22770609 MOAD: Ki=4.7uM
    PDBbind: -logKd/Ki=5.37, Ki=4.3uM
    BindingDB: Ki=4700nM
    12871 4el9:A (1.55) BS01 AFE 2.7.11.1 GO:0004672 ... P18654 22846040 PDBbind: -logKd/Ki=5.36, IC50=4.37uM
    12872 4elb:A (2.6) BS01 34S 1.5.1.3 GO:0000166 ... Q81R22 22999981 PDBbind: -logKd/Ki=8.30, Ki=5.0nM
    12873 4ele:A (2.35) BS02 31I 1.5.1.3 GO:0000166 ... Q81R22 22999981 MOAD: Ki=13.2nM
    PDBbind: -logKd/Ki=7.88, Ki=13.2nM
    12874 4elf:A (2.3) BS02 35I 1.5.1.3 GO:0000166 ... Q81R22 22999981 MOAD: Ki=9.4nM
    PDBbind: -logKd/Ki=8.03, Ki=9.4nM
    12875 4elg:A (2.101) BS01 52J 1.5.1.3 GO:0000166 ... Q81R22 22999981 MOAD: Ki=6.9nM
    PDBbind: -logKd/Ki=8.16, Ki=6.9nM
    12876 4elh:A (2.103) BS02 53I 1.5.1.3 GO:0000166 ... Q81R22 22999981 MOAD: Ki=8.2nM
    PDBbind: -logKd/Ki=8.09, Ki=8.2nM
    12877 4em7:A (1.9) BS01 0RA N/A GO:0003677 ... N/A 22814212 MOAD: ic50=7.7uM
    PDBbind: -logKd/Ki=5.11, IC50=7.7uM
    12878 4emf:A (1.77) BS01 M7G 3.2.2.22 GO:0000166 ... D9J2T9 23280611 PDBbind: -logKd/Ki=7.08, Kd=83.9nM
    12879 4emr:A (1.75) BS01 MGP 3.2.2.22 GO:0000166 ... D9J2T9 23280611 PDBbind: -logKd/Ki=7.49, Kd=32.1nM
    12880 4emt:A (1.5) BS01 C2E ? GO:0002218 ... Q86WV6 22728658 Manual survey: Kd=5uM (22728658)
    MOAD: Kd=4.63uM
    PDBbind: -logKd/Ki=5.30, Kd~5uM
    BindingDB: EC50=4500nM, Kd=1210nM
    12881 4emt:B (1.5) BS01 C2E ? GO:0002218 ... Q86WV6 22728658 Manual survey: Kd=5uM (22728658)
    PDBbind: -logKd/Ki=5.30, Kd~5uM
    BindingDB: EC50=4500nM, Kd=1210nM
    12882 4emv:A (1.7) BS01 0R9 N/A GO:0003677 ... N/A 22814212 MOAD: ic50=0.005uM
    PDBbind: -logKd/Ki=8.30, IC50=0.005uM
    12883 4en4:A (2.15) BS02 GT0 2.7.1.35 GO:0000287 ... O00764 22879864 MOAD: Ki=3uM
    PDBbind: -logKd/Ki=5.52, Ki=3uM
    12884 4enj:A (3.0989) BS01 dna ? GO:0003677 ... Q9UTN9 22658721 PDBbind: Kd=0.29nM
    12885 4enj:A (3.0989) BS02 dna ? GO:0003677 ... Q9UTN9 22658721 PDBbind: Kd=0.29nM
    12886 4enk:A (3.0445) BS01 dna ? GO:0003677 ... Q9UTN9 22658721 PDBbind: Kd=0.07nM
    12887 4enk:A (3.0445) BS02 dna ? GO:0003677 ... Q9UTN9 22658721 PDBbind: Kd=0.07nM
    12888 4enm:A (2.8402) BS01 dna ? GO:0003677 ... Q9UTN9 22658721 PDBbind: Kd=0.08nM
    12889 4enm:A (2.8402) BS02 dna ? GO:0003677 ... Q9UTN9 22658721 PDBbind: Kd=0.08nM
    12890 4enn:A (2.8448) BS01 dna ? GO:0003677 ... Q9UTN9 22658721 PDBbind: Kd=0.71nM
    12891 4enn:A (2.8448) BS02 dna ? GO:0003677 ... Q9UTN9 22658721 PDBbind: Kd=0.71nM
    12892 4enn:B (2.8448) BS01 dna ? GO:0003677 ... Q9UTN9 22658721 PDBbind: Kd=0.71nM
    12893 4enn:B (2.8448) BS02 dna ? GO:0003677 ... Q9UTN9 22658721 PDBbind: Kd=0.71nM
    12894 4enx:A (2.8) BS01 Z20 2.7.11.1 GO:0004672 ... P11309 22869110 PDBbind: -logKd/Ki=6.26, IC50=0.550uM
    12895 4eny:A (2.801) BS01 J19 2.7.11.1 GO:0004672 ... P11309 22869110 PDBbind: -logKd/Ki=7.05, IC50=0.089uM
    12896 4eo4:A (2.87) BS01 SSA 6.1.1.3 GO:0000166 ... P07236 22773845 PDBbind: -logKd/Ki=6.35, Ki=450nM
    12897 4eo4:A (2.87) BS02 SSA 6.1.1.3 GO:0000166 ... P07236 22773845 PDBbind: -logKd/Ki=6.35, Ki=450nM
    12898 4eo6:A (1.791) BS01 0S2 2.7.7.48
    3.4.21.98
    3.4.22.-
    3.6.1.15
    3.6.4.13    		 GO:0003723 ... P26663 22664130 MOAD: Kd=0.002uM
    PDBbind: -logKd/Ki=8.70, Kd=2nM
    12899 4eo8:A (1.798) BS01 0S3 2.7.7.48
    3.4.21.98
    3.4.22.-
    3.6.1.15
    3.6.4.13    		 GO:0003723 ... P26663 22664130 MOAD: Kd=0.007uM
    PDBbind: -logKd/Ki=8.15, Kd=7nM
    12900 4eoh:A (2.1) BS01 TEP 2.7.1.35 GO:0000287 ... O00764 22879864 MOAD: Ki=50uM
    PDBbind: -logKd/Ki=4.30, Ki=50uM
    12901 4eoi:A (2.0) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 PDBbind: -logKd/Ki=6.05, Ki=0.89uM
    BindingDB: IC50=253nM, Ki=340nM
    12902 4eok:A (2.57) BS01 4SP 2.7.11.22 GO:0000082 ... P24941 22921070 PDBbind: -logKd/Ki=5.07, Ki=8600nM
    BindingDB: IC50=6.0nM, Ki=6.0nM, Kd=1310nM
    12903 4eol:A (2.4) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 PDBbind: -logKd/Ki=6.05, Ki=0.89uM
    BindingDB: IC50=253nM, Ki=340nM
    12904 4eon:A (2.4) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 PDBbind: -logKd/Ki=6.05, Ki=0.89uM
    BindingDB: IC50=253nM, Ki=340nM
    12905 4eop:A (1.99) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 PDBbind: -logKd/Ki=6.05, Ki=0.89uM
    BindingDB: IC50=253nM, Ki=340nM
    12906 4eor:A (2.2) BS01 4SP 2.7.11.22 GO:0000082 ... P24941 22921070 MOAD: Ki=500nM
    PDBbind: -logKd/Ki=6.30, Ki=500nM
    BindingDB: IC50=6.0nM, Ki=6.0nM, Kd=1310nM
    12907 4eos:A (2.57) BS01 1RO 2.7.11.22 GO:0000082 ... P24941 22921070 PDBbind: -logKd/Ki=6.05, Ki=0.89uM
    BindingDB: IC50=253nM, Ki=340nM
    12908 4eot:A (2.855) BS01 dna ? GO:0003677 ... Q8NHW3 23148532 PDBbind: Kd=0.46nM
    12909 4eot:A (2.855) BS02 dna ? GO:0003677 ... Q8NHW3 23148532 PDBbind: Kd=0.46nM
    12910 4eot:B (2.855) BS01 dna ? GO:0003677 ... Q8NHW3 23148532 PDBbind: Kd=0.46nM
    12911 4eot:B (2.855) BS02 dna ? GO:0003677 ... Q8NHW3 23148532 PDBbind: Kd=0.46nM
    12912 4eox:P (1.783) BS01 0S5 3.5.1.88 GO:0006412 ... Q8DP79 22579486 MOAD: ic50=0.28nM
    PDBbind: -logKd/Ki=9.55, IC50=0.28nM
    12913 4epy:A (1.801) BS02 0QY 3.6.5.2 GO:0003924 ... P01116 22566140 MOAD: Kd=340uM
    PDBbind: -logKd/Ki=3.47, Kd=340uM
    12914 4eqc:A (2.01) BS01 XR1 2.7.11.1 GO:0004672 ... Q13153 23960073 MOAD: ic50=8nM
    PDBbind: -logKd/Ki=8.10, IC50=8nM
    BindingDB: IC50=2.8nM
    12915 4er1:E (2.0) BS01 0ZP 3.4.23.22 GO:0004190 ... P11838 6381096 MOAD: Ki=0.24uM
    PDBbind: -logKd/Ki=6.62, Ki=0.242uM
    12916 4erd:A (2.589) BS01 rna ? GO:0003723 ... W7X6T2 22705372 PDBbind: Kd=101nM
    12917 4erd:A (2.589) BS02 rna ? GO:0003723 ... W7X6T2 22705372 PDBbind: Kd=101nM
    12918 4erd:B (2.589) BS01 rna ? GO:0003723 ... W7X6T2 22705372 PDBbind: Kd=101nM
    12919 4erd:B (2.589) BS02 rna ? GO:0003723 ... W7X6T2 22705372 PDBbind: Kd=101nM
    12920 4ere:A (1.8) BS01 0R2 2.3.2.27 GO:0005634 ... Q00987 22524527 MOAD: ic50=4.2nM
    PDBbind: -logKd/Ki=8.38, IC50=4.2nM
    12921 4erf:A (2.0) BS01 0R3 2.3.2.27 GO:0005634 ... Q00987 22524527 MOAD: Kd=0.4nM
    PDBbind: -logKd/Ki=9.40, Kd=0.4nM
    BindingDB: Kd=0.4nM, IC50=4.1nM
    12922 4erk:A (2.2) BS01 OLO 2.7.11.24 GO:0000165 ... P63086 9753691 MOAD: ic50=27uM
    PDBbind: -logKd/Ki=4.57, IC50=27uM
    BindingDB: IC50=27000nM
    12923 4erw:A (2.0) BS01 STU 2.7.11.22 GO:0000082 ... P24941 22893598 PDBbind: -logKd/Ki=8.15, IC50=7nM
    12924 4esi:A (1.87) BS01 0RB 3.2.2.22 GO:0017148 ... P02879 23050058 MOAD: ic50=70uM
    PDBbind: -logKd/Ki=4.15, IC50=70uM
    12925 4etz:A (2.05) BS01 C2E ? N/A Q9HZE7 22810222 Manual survey: Kd=0.5uM (22810222)
    MOAD: Kd~0.5uM
    PDBbind: -logKd/Ki=6.30, Kd=0.5uM
    12926 4eu0:A (1.7) BS01 C2E ? N/A Q9HZE7 22810222 Manual survey: Kd=0.5uM (22810222)
    MOAD: Kd=0.4uM
    PDBbind: -logKd/Ki=6.40, Kd=0.4uM
    12927 4eu3:B (1.58) BS01 CIT 2.8.3.18 GO:0003986 ... B3EY95 23030530 PDBbind: -logKd/Ki=0.82, Ki=150mM
    12928 4euc:A (2.644) BS01 0RQ 2.8.3.18 GO:0003986 ... B3EY95 23030530 PDBbind: -logKd/Ki=6.10, Kd=0.8uM
    12929 4euc:B (2.644) BS01 0RQ 2.8.3.18 GO:0003986 ... B3EY95 23030530 PDBbind: -logKd/Ki=6.10, Kd=0.8uM
    12930 4euo:A (1.28) BS01 ABU ? GO:0042597 ... A9CGA5 23043322 PDBbind: -logKd/Ki=5.05, Kd=9uM
    12931 4euv:A (2.0) BS01 C2E ? N/A Q9HZE7 22810222 Manual survey: Kd=0.5uM (22810222)
    MOAD: Kd~0.5uM
    PDBbind: -logKd/Ki=6.30, Kd=0.5uM
    12932 4ew2:A (1.602) BS01 DXY 2.1.2.2
    6.3.3.1
    6.3.4.13    		 GO:0004644 ... P22102 23869564 PDBbind: -logKd/Ki=6.68, Ki=0.21uM
    12933 4ew3:A (1.702) BS01 DXZ 2.1.2.2
    6.3.3.1
    6.3.4.13    		 GO:0004644 ... P22102 23869564 MOAD: Ki=0.18uM
    PDBbind: -logKd/Ki=6.74, Ki=0.18uM
    12934 4ewh:A (2.5) BS01 T77 2.7.10.2
    2.7.11.1    		 GO:0004672 ... Q07912 22929232 MOAD: Ki=0.0003uM
    PDBbind: -logKd/Ki=9.52, Ki=0.3nM
    BindingDB: Ki=0.3nM
    12935 4ewn:D (1.903) BS01 0VR 4.3.2.10 GO:0000105 ... Q9X0C6 23109729 MOAD: Kd=0.2uM
    PDBbind: -logKd/Ki=6.70, Kd=0.2uM
    12936 4ewo:A (1.8) BS01 996 3.4.23.46 GO:0004190 ... P56817 23010268 MOAD: ic50=44nM
    PDBbind: -logKd/Ki=7.36, IC50=44nM
    12937 4exg:A (1.8) BS01 916 3.4.23.46 GO:0004190 ... P56817 23010268 MOAD: ic50=8.5nM
    PDBbind: -logKd/Ki=8.07, IC50=8.5nM
    12938 4exs:B (2.4) BS01 X8Z 3.5.2.6 N/A C7C422 22713171 MOAD: Ki=39uM
    PDBbind: -logKd/Ki=4.41, Ki=39.0uM
    BindingDB: Kd=14000nM, IC50=50119nM
    12939 4exz:A (1.608) BS01 RET ? GO:0005501 ... P50120 23224553 PDBbind: -logKd/Ki=7.54, Kd=29nM
    12940 4eyj:A (2.102) BS01 N61 2.7.11.24 GO:0000165 ... O15264 23187130 PDBbind: -logKd/Ki=6.21, IC50=620nM
    BindingDB: IC50=619.5nM
    12941 4eym:A (2.353) BS01 0RX 2.7.11.24 GO:0000165 ... O15264 23187130 PDBbind: -logKd/Ki=4.01, IC50=98747nM
    BindingDB: IC50=14884nM
    12942 4eyr:A (1.8) BS01 RIT 3.1.26.13 GO:0004190 ... Q000H7 23313846 PDBbind: -logKd/Ki=6.63, IC50=237nM
    12943 4eyr:B (1.8) BS01 RIT 3.1.26.13 GO:0004190 ... Q000H7 23313846 MOAD: ic50=237nM
    PDBbind: -logKd/Ki=6.63, IC50=237nM
    12944 4ez3:A (2.0) BS01 0S0 2.7.11.22 GO:0000082 ... P24941 22893598 PDBbind: -logKd/Ki=4.35, IC50=45uM
    12945 4ez5:A (2.7) BS01 0RS 2.7.11.22 GO:0000082 ... Q00534 24900493 PDBbind: -logKd/Ki=6.52, IC50=0.3uM
    BindingDB: IC50=300nM
    12946 4ezj:A (2.67) BS01 0SC 2.7.11.1
    2.7.1.137
    2.7.1.153
    2.7.1.154    		 GO:0016301 ... P48736 22672799 PDBbind: -logKd/Ki=8.42, IC50=3.8nM
    BindingDB: IC50=1585nM
    12947 4ezk:A (2.803) BS01 0SD 2.7.11.1
    2.7.1.137
    2.7.1.153
    2.7.1.154    		 GO:0016301 ... P48736 22672799 PDBbind: -logKd/Ki=8.20, IC50=6.3nM
    12948 4ezl:A (2.94) BS01 0SE 2.7.11.1
    2.7.1.137
    2.7.1.153
    2.7.1.154    		 GO:0016301 ... P48736 22672799 PDBbind: -logKd/Ki=8.59, IC50=2.6nM
    12949 4f08:A (2.82) BS01 1RS 2.7.10.2 GO:0004672 ... O60674 22698084 PDBbind: -logKd/Ki=6.60, Ki=250nM
    BindingDB: Ki=250nM, EC50=>8800nM
    12950 4f09:A (2.4) BS01 JAK 2.7.10.2 GO:0004672 ... O60674 22698084 MOAD: Ki=200nM
    PDBbind: -logKd/Ki=6.70, Ki=200nM
    BindingDB: Ki=200nM, EC50=>8200nM
    12951 4f0c:A (1.901) BS01 GDS ? GO:0016740 ... I7B368 26348000 PDBbind: -logKd/Ki=6.27, Kd=0.54uM
    12952 4f1l:A (1.9) BS01 0RY 2.4.2.- GO:0003950 ... Q460N5 22823910 PDBbind: -logKd/Ki=5.12, Kd=7.6uM
    BindingDB: IC50=>20000nM, Kd=7600nM
    12953 4f1q:A (2.8) BS01 0RZ 2.4.2.- GO:0003950 ... Q460N5 22823910 PDBbind: -logKd/Ki=4.95, Kd=11.2uM
    BindingDB: IC50=>20000nM, Kd=11200nM
    12954 4f1s:A (3.0) BS01 F1S 2.7.11.1
    2.7.1.137
    2.7.1.153
    2.7.1.154    		 GO:0016301 ... P48736 22832322 PDBbind: -logKd/Ki=8.70, Ki=2.0nM
    12955 4f2j:C (2.64) BS01 dna ? N/A O75362 23436653 PDBbind: Kd=25nM
    12956 4f2w:A (2.0) BS01 TDI N/A GO:0003824 ... N/A 23685211 MOAD: Ki=5pM
    PDBbind: -logKd/Ki=11.30, Ki=5.0pM
    12957 4f2w:B (2.0) BS01 TDI N/A GO:0003824 ... N/A 23685211 MOAD: Ki=5pM
    PDBbind: -logKd/Ki=11.30, Ki=5.0pM
    12958 4f39:A (1.834) BS01 KAI ? GO:0015276 ... P19492 22512472 MOAD: Ki=3.44uM
    PDBbind: -logKd/Ki=5.70, Ki=1980nM
    BindingDB: EC50=40000nM, Ki=5780nM
    12959 4f3c:A (1.93) BS01 BIG N/A GO:0003824 ... N/A 23685211 MOAD: Ki=1.5pM
    PDBbind: -logKd/Ki=11.82, Ki=1.5pM
    12960 4f3c:B (1.93) BS01 BIG N/A GO:0003824 ... N/A 23685211 MOAD: Ki=1.5pM
    PDBbind: -logKd/Ki=11.82, Ki=1.5pM
    12961 4f3h:A (2.5) BS01 C2E ? N/A Q8P8F1 22993092 PDBbind: -logKd/Ki=6.38, Kd=0.42uM
    12962 4f3i:A (1.4) BS01 0S6 ? N/A O60885 22645123 MOAD: Kd=36.1nM
    PDBbind: -logKd/Ki=7.44, Kd=36.1nM
    BindingDB: Ki=17nM, IC50=18.2nM
    12963 4f3k:A (1.85) BS01 HCE N/A GO:0003824 ... N/A 23685211 MOAD: Ki=69pM
    PDBbind: -logKd/Ki=10.16, Ki=69.0pM
    12964 4f3k:A (1.85) BS02 HCE N/A GO:0003824 ... N/A 23685211 MOAD: Ki=69pM
    PDBbind: -logKd/Ki=10.16, Ki=69.0pM
    12965 4f3k:B (1.85) BS01 HCE N/A GO:0003824 ... N/A 23685211 MOAD: Ki=69pM
    PDBbind: -logKd/Ki=10.16, Ki=69.0pM
    12966 4f49:A (2.25) BS01 K36 3.4.19.12
    3.4.22.-    		 GO:0008233 ... P0C6V2 22915796 PDBbind: -logKd/Ki=6.09, IC50=0.82uM
    12967 4f4p:A (2.37) BS01 0SB 2.7.10.2 GO:0004672 ... P43405 22877633 MOAD: ic50=0.6nM
    PDBbind: -logKd/Ki=9.22, IC50=0.6nM
    12968 4f5y:A (2.396) BS02 C2E ? GO:0002218 ... Q86WV6 22728660 Manual survey: Kd=3.7uM (22728660)
    PDBbind: -logKd/Ki=5.43, Kd=3.70uM
    BindingDB: EC50=4500nM, Kd=1210nM
    12969 4f5y:B (2.396) BS01 C2E ? GO:0002218 ... Q86WV6 22728660 Manual survey: Kd=3.7uM (22728660)
    PDBbind: -logKd/Ki=5.43, Kd=3.70uM
    BindingDB: EC50=4500nM, Kd=1210nM
    12970 4f63:A (2.55) BS01 0S7 2.7.10.1 GO:0004672 ... P11362 22612866 PDBbind: -logKd/Ki=6.30, IC50=0.5uM
    BindingDB: IC50=501.19nM
    12971 4f64:A (2.05) BS01 0S8 2.7.10.1 GO:0004672 ... P11362 22612866 MOAD: ic50=63nM
    PDBbind: -logKd/Ki=7.20, IC50=63.1nM
    BindingDB: IC50=794.33nM
    12972 4f65:A (2.26) BS01 0S9 2.7.10.1 GO:0004672 ... P11362 22612866 MOAD: ic50=2.5nM
    PDBbind: -logKd/Ki=8.60, IC50=2.5nM
    BindingDB: IC50=63.1nM
    12973 4f6n:A (2.8) BS01 dna ? N/A Q86T24 22949637 PDBbind: Kd=190pM
    12974 4f6n:A (2.8) BS02 dna ? N/A Q86T24 22949637 PDBbind: Kd=190pM
    12975 4f6s:A (2.6) BS01 0SQ 2.7.11.22
    2.7.11.23    		 GO:0004672 ... P49336 23630251 PDBbind: -logKd/Ki=5.49, Kd=3.24uM
    12976 4f6u:A (2.1) BS01 0SR 2.7.11.22
    2.7.11.23    		 GO:0004672 ... P49336 23630251 PDBbind: -logKd/Ki=6.15, Kd=0.70uM
    12977 4f6v:A (2.3) BS01 ZYM 2.5.1.96 GO:0003824 ... A9JQL9 22662288 MOAD: ic50=24uM
    PDBbind: -logKd/Ki=5.80, IC50=1.6uM
    BindingDB: IC50=24000nM, Ki=250nM
    12978 4f6w:A (2.39) BS01 0SS 2.7.11.22
    2.7.11.23    		 GO:0004672 ... P49336 23630251 PDBbind: -logKd/Ki=7.52, Kd=0.03uM
    12979 4f6x:A (1.98) BS01 ZYL 2.5.1.96 GO:0003824 ... A9JQL9 22662288 MOAD: ic50=45.3uM
    PDBbind: -logKd/Ki=5.09, IC50=8.2uM
    BindingDB: IC50=45300nM, Ki=450nM
    12980 4f70:A (3.0) BS01 0ST 2.7.11.22
    2.7.11.23    		 GO:0004672 ... P49336 23630251 PDBbind: -logKd/Ki=5.74, Kd=1.82uM
    12981 4f7j:A (2.6) BS01 0SU 2.7.11.22
    2.7.11.23    		 GO:0004672 ... P49336 23630251 PDBbind: -logKd/Ki=5.24, Kd=5.82uM
    12982 4f7l:A (2.9) BS01 0SO 2.7.11.22
    2.7.11.23    		 GO:0004672 ... P49336 23630251 PDBbind: -logKd/Ki=8.00, Kd=0.01uM
    12983 4f7n:A (2.65) BS01 0SV 2.7.11.22
    2.7.11.23    		 GO:0004672 ... P49336 23630251 PDBbind: -logKd/Ki=7.10, Kd=0.08uM
    12984 4f7v:A (1.73) BS01 J1D 2.7.6.3 GO:0000287 ... P26281 22727779 MOAD: Kd=4.16uM
    PDBbind: -logKd/Ki=5.38, Kd=4.16uM
    BindingDB: IC50=9530nM, Kd=4160nM
    12985 4f8h:A (2.99) BS01 RKE ? GO:0004888 ... Q7NDN8 22958642 PDBbind: -logKd/Ki=4.24, IC50=58uM
    12986 4f8h:A (2.99) BS03 RKE ? GO:0004888 ... Q7NDN8 22958642 PDBbind: -logKd/Ki=4.24, IC50=58uM
    12987 4f8h:B (2.99) BS01 RKE ? GO:0004888 ... Q7NDN8 22958642 PDBbind: -logKd/Ki=4.24, IC50=58uM
    12988 4f8h:B (2.99) BS02 RKE ? GO:0004888 ... Q7NDN8 22958642 PDBbind: -logKd/Ki=4.24, IC50=58uM
    12989 4f9g:A (2.95) BS01 C2E ? GO:0002218 ... Q86WV6 22705373 Manual survey: Km=2.4+-0.5mM (22705373)
    PDBbind: -logKd/Ki=5.62, Kd=2.4uM
    BindingDB: EC50=4500nM, Kd=1210nM
    12990 4f9g:C (2.95) BS01 C2E ? GO:0002218 ... Q86WV6 22705373 Manual survey: Km=2.4+-0.5mM (22705373)
    PDBbind: -logKd/Ki=5.62, Kd=2.4uM
    BindingDB: EC50=4500nM, Kd=1210nM
    12991 4f9u:A (1.8) BS02 PBD 2.3.2.5 GO:0005576 ... Q9VRQ9 22897232 MOAD: Ki=3139nM
    PDBbind: -logKd/Ki=6.03, Ki=944nM
    12992 4f9v:A (2.1) BS02 PBD 2.3.2.5 GO:0005576 ... Q9VRQ9 22897232 PDBbind: -logKd/Ki=6.03, Ki=944nM
    12993 4f9v:A (2.1) BS03 PBD 2.3.2.5 GO:0005576 ... Q9VRQ9 22897232 PDBbind: -logKd/Ki=6.03, Ki=944nM
    12994 4f9w:A (2.0) BS03 LM4 2.7.11.24 GO:0000077 ... Q16539 23840427 MOAD: Ki=114nM
    PDBbind: -logKd/Ki=6.94, Ki=114nM
    BindingDB: IC50=210nM, Ki=110nM
    12995 4f9y:A (1.85) BS03 LM3 2.7.11.24 GO:0000077 ... Q16539 23840427 MOAD: Ki=184nM
    PDBbind: -logKd/Ki=6.74, Kd=184nM
    BindingDB: IC50=190nM, Ki=180nM
    12996 4fab:H (2.7) BS01 FLU ? N/A P01865 2508085 PDBbind: -logKd/Ki=8.06, Kd=8.8nM
    12997 4fab:L (2.7) BS01 FLU N/A N/A N/A 2508085 PDBbind: -logKd/Ki=8.06, Kd=8.8nM
    12998 4fai:A (1.65) BS02 PBD 2.3.2.5 GO:0005576 ... Q86PD7 22897232 PDBbind: -logKd/Ki=6.99, Ki=101.3nM
    12999 4fak:A (1.7) BS01 SAM 2.1.1.177 GO:0005737 ... P0C1V0 23150671 PDBbind: -logKd/Ki=4.28, Kd=52uM
    13000 4fb3:A (3.79) BS01 dna 3.6.4.- GO:0003688 ... P0DOJ4 24109229 PDBbind: Kd=38nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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