Structure of PDB 6zxh Chain z

Receptor sequence
>6zxhz (length=349) Species: 9606 (Homo sapiens) [Search protein sequence]
TDSVINKVTEKSRQKEADMYRIKDKADRATVEQVLDPRTRMILFKMLTRG
IITEINGCISTGKEANVYHASTANGESRAIKIYKTSILVFKDRDKYVSGE
FRFRHGYCKGNPRKMVKTWAEKEMRNLIRLNTAEIPCPEPIMLRSHVLVM
SFIGKDDMPAPLLKNVQLSESKARELYLQVIQYMRRMYQDARLVHADLSE
FNMLYHGGGVYIIDVSQSVEHDHPHALEFLRKDCANVNDFFMRHSVAVMT
VRELFEFVTDPSITHENMDAYLSKAMEIASQRTKEERSSQDHVDEEVFKR
AYIPRKNYERDMDIIMKLKEKKERKKMVKEAQREKRKNKIPKHVKKRKE
3D structure
PDB6zxh Structural basis for the final steps of human 40S ribosome maturation.
Chainz
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
3.6.3.-
Interaction with ligand
Gene Ontology
Molecular Function
GO:0004674 protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0044024 histone H2AS1 kinase activity
GO:0046872 metal ion binding
GO:0106310 protein serine kinase activity
Biological Process
GO:0006338 chromatin remodeling
GO:0016310 phosphorylation
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
GO:2000234 positive regulation of rRNA processing
Cellular Component
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0030688 preribosome, small subunit precursor
GO:0034708 methyltransferase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zxh, PDBe:6zxh, PDBj:6zxh
PDBsum6zxh
PubMed33208940
UniProtQ9BRS2|RIOK1_HUMAN Serine/threonine-protein kinase RIO1 (Gene Name=RIOK1)

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