Structure of PDB 8pj5 Chain y

Receptor sequence

>8pj5y (length=531) Species: 9606 (Homo sapiens) [Search protein sequence]

MFAKGTEITHAVVIKKLNEILQARGKKGTDRAAQIELLQLLVQIAAENNL
GEGVIVKIKFNIIASLYDYNPNLATYMKPEMWGKCLDCINELMDILFANP
NIFVGENILEESENLHNADQPLRVRGCILTLVERMDEEFTKIMQNTDPHS
QEYVEHLKDEAQVCAIIERVQRYLEEKGTTEEVCRIYLLRILHTYYKFDY
KAHQRQNEGEDSAVLMERLCKYIYAKDRTDRIRTCAILCHIYHHALHSRW
YQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGLTKDAHNA
LLDIQSSGRAKELLGQGLLLRSLQERNQEQEKVERRRQVPFHLHINLELL
ECVYLVSAMLLEIPYMAAHESDARRRMISKQFHHQLRVGERQPLLGPPES
MREHVVAASKAMKMGDWKTCHSFIINEKMNGKVWDLFPEADKVRTMLVRK
IQEESLRTYLFTYSSVYDSISMETLSDMFELDLPTVHSIISKMIINEELM
ASLDQPTQTVVMHRTEPTAQQNLALQLAEKL

3D structure

PDB

8pj5 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining

Chain

Resolution

2.9 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	y	H465 D635 L650 R653 H716 R719 R723 R734	H149 D303 L318 R321 H384 R387 R391 R402

External links

PDB	RCSB:8pj5, PDBe:8pj5, PDBj:8pj5
PDBsum	8pj5
PubMed
UniProt	Q99613\|EIF3C_HUMAN Eukaryotic translation initiation factor 3 subunit C (Gene Name=EIF3C)

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