Structure of PDB 8pj6 Chain x

Receptor sequence

>8pj6x (length=420) Species: 9606 (Homo sapiens) [Search protein sequence]

VPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSQYAYFHEEDE
SSFQLVDTARTEVKEEMDFPQLMKMRYLEVSEPQDIECCGALEYYDKAFD
RITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLMS
CTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQDEGNSFN
SPRNLAMEATYINHNFSQQCLRMGKERYNFPNPNPFVEDDMDKNEIASVA
YRYRRWKLGDDIDLIVRCEHDGVMTGANGEVSFINIKTLNEWDSRHCNGV
DWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLKLGYVSRYHV
KDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYL
ILKDPNKQVIRVYSLPDGTF

3D structure

PDB

8pj6 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining

Chain

Resolution

2.9 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	x	T49 Q51 K53	T29 Q31 K33
BS02	rna	x	T85 A86 R87 T88 Q411	T58 A59 R60 T61 Q304

External links

PDB	RCSB:8pj6, PDBe:8pj6, PDBj:8pj6
PDBsum	8pj6
PubMed
UniProt	O15371\|EIF3D_HUMAN Eukaryotic translation initiation factor 3 subunit D (Gene Name=EIF3D)

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