Structure of PDB 8oeq Chain x

Receptor sequence

>8oeqx (length=173) Species: 5476 (Candida albicans) [Search protein sequence]

VRYAATPANPAKSASARGSYLRVSFKNTRETAQAINGWKLEKAQKYLDQV
LDHQRAIPFRRYNSSIGRTGQGKEFGVTKARWPAKSVNFVKDLLRNAQAN
AEAKGLDSSKLVISHIQVNHAPKQRRRTYRAHGRINAYQSTPSHIELTLT
EEDEQIRLNSRQRGRLASQKRLT

3D structure

PDB

8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement

Chain

Resolution

3.3 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	x	V2 R3 Y4 S16 Y21 R23 S25 F26 K27 R30 Q34 R56 R62 Y63 S65 S66 I67 G68 R69 Q72 K74 E75 T79 K80 R82 W83 P84 A85 K86 R96 N97 A100 N101 Q118 V119 R126 R127 T129 Y130 R131 A132 H133 G134 R135 N137 A138 Y139 Q140 S141 R167 N169 S170 R171 Q172 G174 R175 S178 R181 L182	V1 R2 Y3 S15 Y20 R22 S24 F25 K26 R29 Q33 R55 R61 Y62 S64 S65 I66 G67 R68 Q71 K73 E74 T78 K79 R81 W82 P83 A84 K85 R95 N96 A99 N100 Q117 V118 R125 R126 T128 Y129 R130 A131 H132 G133 R134 N136 A137 Y138 Q139 S140 R157 N159 S160 R161 Q162 G164 R165 S168 R171 L172
BS02	rna	x	R3 A5 R30 R61 R62 N120 H121 P123	R2 A4 R29 R60 R61 N119 H120 P122
BS03	MG	x	S66 I67	S65 I66
BS04	MG	x	G77 V78	G76 V77

External links

PDB	RCSB:8oeq, PDBe:8oeq, PDBj:8oeq
PDBsum	8oeq
PubMed
UniProt	A0A8H6BUG0

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