Structure of PDB 7nac Chain x

Receptor sequence
>7nacx (length=539) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence]
SLEWDNLGFSLLPWIRTGLDVMGFETMTPVQASTIPMLAGNKDVVVDSVT
GSGKTAAFVIPVLEKVVKEEANTSKFKKAHFHSLIIAPTRELSRQIESVV
LSFLEHYPSDLFPIKCQLLVGTNEATVRDDVSNFLRNRPQILIGTPGRVL
DFLQMPAVKTSACSMVVMDEADRLLDMSFIKDTEKILRLLPKQRRTGLFS
ATMRSAGSDIFKTGLRNPVRITVNSSSLKLNYCVVNPAEKLQLLVSILNN
YKFKKCIVYFPTCVSVSYFYSFIQYLGKRNILVNEVEIFSLHGKLQTSAR
TKTLTAFTDSNSVLFTTDVAARGIDIPDVDLVIQLDPPTNTDMFMHRCGR
TGRANRVGKAITFLNEGREEDFIPFMQVKNVELEELDLEVKGITANFYED
FRNWILEDRDRFDKGVKAYVAFIKYYSNHSATSIFRLQSLDYVGIAKLYG
LFRLPRMPEITKYLNWLVDPPVNMDEYKYKDKKREKERQETLKNISLIND
KKKLKSELKKKNLAWSDKTLTKERKLERKEKMSLKRKAI
3D structure
PDB7nac Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Chainx
Resolution3.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0000470 maturation of LSU-rRNA
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0042254 ribosome biogenesis
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0030687 preribosome, large subunit precursor

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7nac, PDBe:7nac, PDBj:7nac
PDBsum7nac
PubMed36482249
UniProtP25808|SPB4_YEAST ATP-dependent rRNA helicase SPB4 (Gene Name=SPB4)

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