Structure of PDB 6fti Chain x

Receptor sequence
>6ftix (length=426) Species: 9615 (Canis lupus familiaris) [Search protein sequence]
FLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIM
SSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGD
TPKDRALFNGAQKLFGMIITIGQSIVYVMSGICLLITIQLFVAGLIVLLL
DELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIA
LFHLLATRTDKVRALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDL
PIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFPVG
GLCHYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKD
VAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLG
AIGSGTGILLAVTIIYQYFEIFVKEQ
3D structure
PDB6fti Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum.
Chainx
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna x K268 R273 R402 R405 K253 R258 R363 R366
BS02 peptide x P22 W34 I37 P49 L50 V157 I161 L168 P18 W30 I33 P45 L46 V142 I146 L153
BS03 peptide x K29 F40 K25 F36
Gene Ontology
Molecular Function
GO:0005048 signal sequence binding
GO:0005515 protein binding
GO:0008320 protein transmembrane transporter activity
GO:0043022 ribosome binding
Biological Process
GO:0006613 cotranslational protein targeting to membrane
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0015031 protein transport
GO:0031204 post-translational protein targeting to membrane, translocation
GO:0039019 pronephric nephron development
GO:0045047 protein targeting to ER
GO:0045048 protein insertion into ER membrane
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005784 Sec61 translocon complex
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6fti, PDBe:6fti, PDBj:6fti
PDBsum6fti
PubMed29519914
UniProtP38377|S61A1_CANLF Protein transport protein Sec61 subunit alpha isoform 1 (Gene Name=SEC61A1)

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