Structure of PDB 8v87 Chain w

Receptor sequence
>8v87w (length=280) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence]
ESLFNLKTAEKTGILNDLAKGKKRMIFTMIKDKDSAADADDLESELNAMY
SDYKTRRSERDAKFRAKQARAITNLISKLKGQEGDHKLSSKARMIFNDPI
FNNVEPFDSDYDSEEEKNQTKKEKHSRDIDIATVEAMTLAHQLALGQKNK
HDLVDEGFNRYTFRDTENLPDWFLEDEKEHSKINKPITKEAAMAIKEKIK
AMNARPIKKVAEAKARKRMRAVARLEKIKKKAGLVTLVVASGRNKGLAGR
PKGVKGKYKMVDGVMKNEQRALRRIAKKHH
3D structure
PDB8v87 The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis.
Chainw
Resolution2.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.167: 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008649 rRNA methyltransferase activity
GO:0008650 rRNA (uridine-2'-O-)-methyltransferase activity
GO:0016435 rRNA (guanine) methyltransferase activity
GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity
Biological Process
GO:0000451 rRNA 2'-O-methylation
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001510 RNA methylation
GO:0006364 rRNA processing
GO:0031167 rRNA methylation
GO:0032259 methylation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8v87, PDBe:8v87, PDBj:8v87
PDBsum8v87
PubMed38632236
UniProtP25582|SPB1_YEAST 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase (Gene Name=SPB1)

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