Structure of PDB 8fzd Chain w

Receptor sequence

>8fzdw (length=349) Species: 562 (Escherichia coli) [Search protein sequence]

KPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQLSDVSRC
FTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVDDE
RNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGG
YKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPE
LPDAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQ
DERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRNLLGSGDRSDRNR
TYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIEPIIQEHQADQLAALS

3D structure

PDB

8fzd The ribosome termination complex remodels release factor RF3 and ejects GDP.

Chain

Resolution

3.1 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	w	M74 G118 R183 S192 G194 G301 D302 R303 R306 Q314 R316	M73 G110 R175 S184 G186 G293 D294 R295 R298 Q306 R308
BS02	rna	w	E155 G233 G234 R261	E147 G225 G226 R253
BS03	rna	w	G120 D122 P188 T190 Q193 R195 I196 H197 T198	G112 D114 P180 T182 Q185 R187 I188 H189 T190
BS04	rna	w	Q32 R36 S39 R40 F227 R228 S229 G231 A232 G234 H236 N238 T239 T240 D241 R245 R261 Q263 H264 R294 R295	Q31 R35 S38 R39 F219 R220 S221 G223 A224 G226 H228 N230 T231 T232 D233 R237 R253 Q255 H256 R286 R287

Gene Ontology

	Molecular Function
GO:0016149	translation release factor activity, codon specific

	Biological Process
GO:0006412	translation
GO:0006415	translational termination

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:8fzd, PDBe:8fzd, PDBj:8fzd
PDBsum	8fzd
PubMed	39030416
UniProt	C3TCZ2

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