Structure of PDB 7w0h Chain w

Receptor sequence
>7w0hw (length=320) Species: 9823 (Sus scrofa) [Search protein sequence]
LQYGPLAFVLGERTTRKLTETSKVITVDGNICSGKGRLAREIAEKLGLRH
FPEAGIHYADSTTGDGKPLDVQLSGNCSLEKFYDDPKSNDGNSYRLQSWL
YASRLLQYADALEHLLSTGQGVVLERSIYSDFVFLEAMYRQGFIRKQCVE
HYNEVKKVTACEYLPPHVVVYVDVPVPEIQSRIQKKGNPHEMKITAAYLQ
DIENAYKKTFLPEMSEKCEVLQYSAREAEDAEKVVEDIEYLKCDKGPWPD
QDDRTFHRLRMLVQNKLEVLNYTTIPVYLPEITIGAHQSDRVFQKFTELP
GRKYSPGYNEDVGDKWIWLK
3D structure
PDB7w0h The coupling mechanism of mammalian mitochondrial complex I.
Chainw
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP w I66 C67 K70 L114 Y118 Q132 L135 R139 R161 F169 M173 I31 C32 K35 L79 Y83 Q97 L100 R104 R126 F134 M138
Gene Ontology
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0045271 respiratory chain complex I

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7w0h, PDBe:7w0h, PDBj:7w0h
PDBsum7w0h
PubMed35145322
UniProtF1SIS9

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