Structure of PDB 8gzu Chain v1

Receptor sequence
>8gzuv1 (length=442) Species: 312017 (Tetrahymena thermophila SB210) [Search protein sequence]
RSYGNLKDQDRIFTNLYRDGDPFVKGALKRGDWHQTKEILSNGPEWIIDE
IKKSGLRGRGGAGFLSGLKYSFMPKVNPDGRPSYLVINSDESEPGTCKDR
EILRNDPHKLVEGALVVGFSMRARAAYIYIRGEFWVEANILQQAIDEAYA
KGFIGKNACGSGYDFDVYIHRGAGAYICGEETGLIESIEGKAGQPRVKPP
FPANAGLYGCPTTVTNVETVAVCPTIMRRGASWFASFGRPNNAGTKLYCI
SGHVNNPCTVEEEMSIPLRELLEKHCGGVRGGWDNLLAVIPGGSSVPMMP
KNVCDDVLMDFDALKAVGSGLGTAAVIVMDKSTDPIDAILRLSKFYKHES
CGQCTPCREGTGWIVDVMERLLVGNADYAEIDMLQQVTQQIEMHTICALG
DAAAWPVQGLIKNFREEIEDRIDSYHAKHPQLKKSRKSNPQI
3D structure
PDB8gzu Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Chainv1
Resolution4.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 v1 P224 S379 C380 G381 Q382 C383 C386 I425 C426 L428 G429 P195 S350 C351 G352 Q353 C354 C357 I396 C397 L399 G400
BS02 FMN v1 G87 G89 Y205 G208 E209 E210 N245 L428 G58 G60 Y176 G179 E180 E181 N216 L399
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0010181 FMN binding
GO:0046872 metal ion binding
GO:0051287 NAD binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8gzu, PDBe:8gzu, PDBj:8gzu
PDBsum8gzu
PubMed37248254
UniProtQ23KE4

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