Structure of PDB 8uu7 Chain v

Receptor sequence

>8uu7v (length=416) Species: 169963 (Listeria monocytogenes EGD-e)

KKVLIVGISQKQKDFDYSMEELANLAAANNMEVVGEIRQNIDRENRATYV
GKGKVDEIKGLAEMQDARLIIFNDELSPSQIRNLEEALELDVMDRTGLIL
AIFANRAKTKEAQLQVQIAKLQYELPRIFGQGEDMDQQSGKGGLSNRGSG
EKKIETDRRTIKHQIRHLQKELDMLVDDREVRRRKRKKNEIPVVSLVGYT
NAGKSTTMNGLVRAYSETADKQVFEKDMLFATLETSVREIVLPDNKQFLL
TDTVGFVSKLPHQLVKAFRSTLEEARDADLLIHVVDYSDPHYKTMMKTTE
ETLKVVGVEDVPVIYAYNKADLLEDEMYPKQTGNTIIFSAREEESLEFLT
EVIRKELFASYEKATFLIPFEAGQVVAYLNEHADILETEYLENGTQIVAE
VSPADLQKLAEYQVAE

3D structure

• PDB: 8uu7 Mechanistic insights into the alternative ribosome recycling by HflXr.
• Chain: v
• Resolution: 3.2 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	v	S11 Q14 K15 D44 R45 R48 A49 K54 G55 K56 S81 K110 P128 M137 D138 S141 L146 S147 R149 G150 S151 G152 E153 K154 K155 E157 R161 K164 V183 R184 R186 K187 V239 R240 Q376 V378 A379 N382 E383 K410	S9 Q12 K13 D42 R43 R46 A47 K52 G53 K54 S79 K108 P126 M135 D136 S139 L144 S145 R147 G148 S149 G150 E151 K152 K153 E155 R159 K162 V181 R182 R184 K185 V237 R238 Q374 V376 A377 N380 E381 K408

Gene Ontology

Molecular Function

• GO:0003924 GTPase activity
• GO:0005525 GTP binding
• GO:0043022 ribosome binding
• GO:0046872 metal ion binding

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:8uu7, PDBe:8uu7, PDBj:8uu7
• PDBsum: 8uu7
• PubMed: 38407413
• UniProt: Q8Y8Y0