Structure of PDB 8qu5 Chain v

Receptor sequence
>8qu5v (length=69) Species: 9606 (Homo sapiens) [Search protein sequence]
APWSREAVLSLYRALLRQGRQLRYTDRDFYFASIRREFRKNQKLEDAEAR
ERQLEKGLVFLNGKLGRII
3D structure
PDB8qu5 GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Chainv
Resolution2.42 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PNS v R6 N42 Q43 E46 A50 R51 Q54 L55 R5 N41 Q42 E45 A49 R50 Q53 L54
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0140978 mitochondrial large ribosomal subunit binding
Biological Process
GO:0000266 mitochondrial fission
GO:0006417 regulation of translation
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0042254 ribosome biogenesis
GO:0070131 positive regulation of mitochondrial translation
GO:1902775 mitochondrial large ribosomal subunit assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qu5, PDBe:8qu5, PDBj:8qu5
PDBsum8qu5
PubMed38969660
UniProtL0R8F8|MIDUO_HUMAN Mitochondrial ribosome and complex I assembly factor AltMIEF1 (Gene Name=MIEF1)

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